AML cell line sensitivity to DTU2GMCSF, DTU2GMCSF plus pro-uPA, and DT388GMCSF as determined by 3H-thymidine incorporation inhibition assays
Cell line . | DTU2GMCSF, IC50, pM . | DTU2GMCSF + pro-uPA, IC50, pM . | DT388GMCSF, IC50, pM . |
|---|---|---|---|
| U937 | 34.7 | 0.48 | 0.47 |
| TF1-vRaf | 3.14 | 0.26 | 0.64 |
| KG-1 | 9.8 | 3.5 | 2.5 |
| HL60 | 7.8 | 1.5 | 2.7 |
| ML2 | 5.8 | 0.76 | 1.9 |
| TF1-vSrc | >4000 | 0.55 | 0.84 |
| TF1-HaRas | >4000 | 0.67 | 0.27 |
| Sig M5 | >4000 | 42 | 21.1 |
| ML1 | >4000 | 30 | 22 |
| ML17 | >4000 | 4.5 | 3.1 |
| Monomac 6 | >4000 | 1730 | 68.3 |
| Monomac 1 | >4000 | >4000 | 3.2 |
| CTV-1 | >4000 | >4000 | >4000 |
Cell line . | DTU2GMCSF, IC50, pM . | DTU2GMCSF + pro-uPA, IC50, pM . | DT388GMCSF, IC50, pM . |
|---|---|---|---|
| U937 | 34.7 | 0.48 | 0.47 |
| TF1-vRaf | 3.14 | 0.26 | 0.64 |
| KG-1 | 9.8 | 3.5 | 2.5 |
| HL60 | 7.8 | 1.5 | 2.7 |
| ML2 | 5.8 | 0.76 | 1.9 |
| TF1-vSrc | >4000 | 0.55 | 0.84 |
| TF1-HaRas | >4000 | 0.67 | 0.27 |
| Sig M5 | >4000 | 42 | 21.1 |
| ML1 | >4000 | 30 | 22 |
| ML17 | >4000 | 4.5 | 3.1 |
| Monomac 6 | >4000 | 1730 | 68.3 |
| Monomac 1 | >4000 | >4000 | 3.2 |
| CTV-1 | >4000 | >4000 | >4000 |