Table 6. Impact of mismatching on... | American Society of Hematology

Table 6.

Impact of mismatching on transplant outcome: impact of additional mismatching on survival among HLA-A, B low-resolution and DRB1 (“6 antigen”) matched pairs

	No.	5-y survival, %
High-resolution matched for 8 of 8 loci	108	39 ± 9
Mismatch at DQ/DP only	683	39 ± 4*
Single class I mismatch	317	31 ± 5†

	No.	5-y survival, %
High-resolution matched for 8 of 8 loci	108	39 ± 9
Mismatch at DQ/DP only	683	39 ± 4*
Single class I mismatch	317	31 ± 5†

Eight locus match includes high-resolution matching for HLA-A, -B, -C, -DRB1, -DQA1, -DQB1, -DPA1, and -DPB1. Class I mismatch refers to high-resolution mismatches for HLA-A and -B and all mismatches for HLA-C.

P = .93 compared to 8 of 8 matched pairs.

†

P = .08 compared to 8 of 8 matched pairs.

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