Relative odds of having a selected medical late effect, a fertility problem, or a functional limitation, or reporting poor health based on donor type, presence or absence of chronic graft-versus-host disease, and sex
. | Odds ratio . | 95% CI . | P . |
|---|---|---|---|
| Hypothyroidism | |||
| Unrelated donor | 0.83 | 0.3-2.0 | .69 |
| Female sex | 1.61 | 0.7-3.6 | .25 |
| Chronic graft-versus-host disease | 3.21 | 1.4-7.5 | .007 |
| Osteoporosis | |||
| Unrelated donor | 0.74 | 0.3-2.1 | .56 |
| Female sex | 2.65 | 1.0-7.2 | .06 |
| Chronic graft-versus-host disease | 2.65 | 1.0-7.2 | .06 |
| Cardiopulmonary impairments | |||
| Unrelated donor | 1.72 | 0.9-3.3 | .10 |
| Female sex | 1.60 | 0.9-2.9 | .12 |
| Chronic graft-versus-host disease | 1.74 | 0.9-3.2 | .07 |
| Impaired sense of touch | |||
| Unrelated donor | 1.20 | 0.6-2.5 | .63 |
| Female sex | 1.33 | 0.7-2.6 | .41 |
| Chronic graft-versus-host disease | 2.11 | 1.1-4.2 | .03 |
| Balance impairment, tremor, or weakness | |||
| Unrelated donor | 1.29 | 0.6-2.7 | .49 |
| Female sex | 1.16 | 0.6-2.3 | .67 |
| Chronic graft-versus-host disease | 2.06 | 1.0-4.1 | .04 |
| Assistance with personal care needed | |||
| Unrelated donor | 0.86 | 0.2-4.4 | .86 |
| Female sex | 3.27 | 0.6-17.8 | .17 |
| Chronic graft-versus-host disease | 1.70 | 0.3-8.1 | .50 |
| Assistance with routine activities needed | |||
| Unrelated donor | 2.64 | 1.0-6.7 | .04 |
| Female sex | 3.40 | 1.3-8.9 | .01 |
| Chronic graft-versus-host disease | 0.73 | 0.3-1.8 | .50 |
| Current health prevents work or school attendance | |||
| Unrelated donor | 2.43 | 1.2-4.9 | .01 |
| Female sex | 1.77 | 0.9-3.5 | .11 |
| Chronic graft-versus-host disease | 1.66 | 0.8-3.3 | .15 |
| Reports poor overall health | |||
| Unrelated donor | 1.42 | 0.7-2.9 | .34 |
| Female sex | 0.84 | 0.4-1.7 | .63 |
| Chronic graft-versus-host disease | 2.41 | 1.2-4.9 | .01 |
. | Odds ratio . | 95% CI . | P . |
|---|---|---|---|
| Hypothyroidism | |||
| Unrelated donor | 0.83 | 0.3-2.0 | .69 |
| Female sex | 1.61 | 0.7-3.6 | .25 |
| Chronic graft-versus-host disease | 3.21 | 1.4-7.5 | .007 |
| Osteoporosis | |||
| Unrelated donor | 0.74 | 0.3-2.1 | .56 |
| Female sex | 2.65 | 1.0-7.2 | .06 |
| Chronic graft-versus-host disease | 2.65 | 1.0-7.2 | .06 |
| Cardiopulmonary impairments | |||
| Unrelated donor | 1.72 | 0.9-3.3 | .10 |
| Female sex | 1.60 | 0.9-2.9 | .12 |
| Chronic graft-versus-host disease | 1.74 | 0.9-3.2 | .07 |
| Impaired sense of touch | |||
| Unrelated donor | 1.20 | 0.6-2.5 | .63 |
| Female sex | 1.33 | 0.7-2.6 | .41 |
| Chronic graft-versus-host disease | 2.11 | 1.1-4.2 | .03 |
| Balance impairment, tremor, or weakness | |||
| Unrelated donor | 1.29 | 0.6-2.7 | .49 |
| Female sex | 1.16 | 0.6-2.3 | .67 |
| Chronic graft-versus-host disease | 2.06 | 1.0-4.1 | .04 |
| Assistance with personal care needed | |||
| Unrelated donor | 0.86 | 0.2-4.4 | .86 |
| Female sex | 3.27 | 0.6-17.8 | .17 |
| Chronic graft-versus-host disease | 1.70 | 0.3-8.1 | .50 |
| Assistance with routine activities needed | |||
| Unrelated donor | 2.64 | 1.0-6.7 | .04 |
| Female sex | 3.40 | 1.3-8.9 | .01 |
| Chronic graft-versus-host disease | 0.73 | 0.3-1.8 | .50 |
| Current health prevents work or school attendance | |||
| Unrelated donor | 2.43 | 1.2-4.9 | .01 |
| Female sex | 1.77 | 0.9-3.5 | .11 |
| Chronic graft-versus-host disease | 1.66 | 0.8-3.3 | .15 |
| Reports poor overall health | |||
| Unrelated donor | 1.42 | 0.7-2.9 | .34 |
| Female sex | 0.84 | 0.4-1.7 | .63 |
| Chronic graft-versus-host disease | 2.41 | 1.2-4.9 | .01 |
Data adjusted for age at transplantation and time since transplantation. Analyses restricted to those who had a related or an unrelated donor and a conditioning regimen that included total body irradiation; n = 206.