Patient characteristics
Characteristic . | Median (range) . | Cut-off . | Percent . |
|---|---|---|---|
| Male | NA | NA | 54 |
| Age, y | 55 (35-71) | > 60 | 28 |
| Serum albumin, g/L | 29 (10-44) | < 20 | 25 |
| Diagnosis to transplantation, months | 4.2 (1.3-75) | ≥ 12 | 12 |
| Creatinine, μM/L [mg/dL] | 97 (53-247) | > 150 | 10 |
| [1.1 (.6-2.8)] | [>1.7] | ||
| Creatinine clearance, mL/s [mL/min] | 1.22 (0.33-2.10) [73 (20-126)] | 1.00 [< 60] | 31 |
| Alkaline phosphatase, IU/L (UNL 300) | 186 (85-2789) | > 1.5 UNL | 17 |
| β2-microglobulin, nM/L [μg/mL] | 201.4 [2.37] (85-858 [1-10.1]) | ≥ 229.5 [2.7] | 31 |
| Serum M spike, g/L | 10 (0-26) | ≥ 20 | 6 |
| Urine total protein, g/24 hours | 3.7 (0.02-26.2) | ≥ 3 | 57 |
| Urine M spike, g/24 hours | 0.17 (0-2.2) | ≥ 1 | 10 |
| Bone marrow plasma cells, % | 6 (.4-49) | > 30 | 5 |
| Bone marrow plasma cell labeling index, % | 0 (0-2.4) | > 1 | 7 |
| Interventricular septal thickness, mm | 12 (7-25) | > 15 | 15 |
| Left ventricular ejection fraction, % | 65 (28-84) | < 55 | 11 |
| Organ systems involved, n | 2 (1-3) | ≥ 3 | 19 |
| Troponin T, μg/L | 0.01 (0-1) | ≥ 0.03 | 14 |
| Troponin I, μg/L* | 0.07 (0-4.31) | ≥ 0.1 | 44 |
| NT-proBNP, ng/L† | 323 (0-35001) | ≥ 332 | 48 |
| Melphalan conditioning | |||
| Mel 200 mg/m2 | NA | NA | 54 |
| Mel 140 mg/m2/TBI | NA | NA | 12 |
| Mel 140 mg/m2 | NA | NA | 24 |
| Mel 100 mg/m2 | NA | NA | 9 |
Characteristic . | Median (range) . | Cut-off . | Percent . |
|---|---|---|---|
| Male | NA | NA | 54 |
| Age, y | 55 (35-71) | > 60 | 28 |
| Serum albumin, g/L | 29 (10-44) | < 20 | 25 |
| Diagnosis to transplantation, months | 4.2 (1.3-75) | ≥ 12 | 12 |
| Creatinine, μM/L [mg/dL] | 97 (53-247) | > 150 | 10 |
| [1.1 (.6-2.8)] | [>1.7] | ||
| Creatinine clearance, mL/s [mL/min] | 1.22 (0.33-2.10) [73 (20-126)] | 1.00 [< 60] | 31 |
| Alkaline phosphatase, IU/L (UNL 300) | 186 (85-2789) | > 1.5 UNL | 17 |
| β2-microglobulin, nM/L [μg/mL] | 201.4 [2.37] (85-858 [1-10.1]) | ≥ 229.5 [2.7] | 31 |
| Serum M spike, g/L | 10 (0-26) | ≥ 20 | 6 |
| Urine total protein, g/24 hours | 3.7 (0.02-26.2) | ≥ 3 | 57 |
| Urine M spike, g/24 hours | 0.17 (0-2.2) | ≥ 1 | 10 |
| Bone marrow plasma cells, % | 6 (.4-49) | > 30 | 5 |
| Bone marrow plasma cell labeling index, % | 0 (0-2.4) | > 1 | 7 |
| Interventricular septal thickness, mm | 12 (7-25) | > 15 | 15 |
| Left ventricular ejection fraction, % | 65 (28-84) | < 55 | 11 |
| Organ systems involved, n | 2 (1-3) | ≥ 3 | 19 |
| Troponin T, μg/L | 0.01 (0-1) | ≥ 0.03 | 14 |
| Troponin I, μg/L* | 0.07 (0-4.31) | ≥ 0.1 | 44 |
| NT-proBNP, ng/L† | 323 (0-35001) | ≥ 332 | 48 |
| Melphalan conditioning | |||
| Mel 200 mg/m2 | NA | NA | 54 |
| Mel 140 mg/m2/TBI | NA | NA | 12 |
| Mel 140 mg/m2 | NA | NA | 24 |
| Mel 100 mg/m2 | NA | NA | 9 |