Table 3. Erythropoiesis in c-Mpl and Kit... | American Society of Hematology

Table 3.

Erythropoiesis in c-Mpl and Kit mutants

	Adult blood			Fetal liver CFU-Es, per 50 000 cells
Genotype	RBC count, × 10¹²/L	Proportion hematocrit		Fetal liver CFU-Es, per 50 000 cells
c-Mpl^+/+Kit^+/+	1.04 ± 0.06	0.479 ± 0.012	192 ± 66
c-Mpl^-/-	1.00 ± 0.02	0.472 ± 0.019	250 ± 90
Kit^Wv/Wv	0.65 ± 0.05*	0.377 ± 0.028*	87
c-Mpl^-/-Kit^Wv/Wv	0.46 ± 0.05*†‡	0.30 ± 0.013*†‡	96 ± 25*†

	Adult blood			Fetal liver CFU-Es, per 50 000 cells
Genotype	RBC count, × 10¹²/L	Proportion hematocrit		Fetal liver CFU-Es, per 50 000 cells
c-Mpl^+/+Kit^+/+	1.04 ± 0.06	0.479 ± 0.012	192 ± 66
c-Mpl^-/-	1.00 ± 0.02	0.472 ± 0.019	250 ± 90
Kit^Wv/Wv	0.65 ± 0.05*	0.377 ± 0.028*	87
c-Mpl^-/-Kit^Wv/Wv	0.46 ± 0.05*†‡	0.30 ± 0.013*†‡	96 ± 25*†

Values are means ± SD.

P < .001 versus wild type.

P < .001 versus c-Mpl^-/-.

P < .001 versus Kit^Wv/Wv.