Outcome and relative risk of death according to risk group as defined by the IPI among the 1647 patients for whom data for the FLIPI and the IPI were available
Risk group . | Number of factors* . | Distribution of patients, % . | 5-year OS, % (SE) . | 10-year OS, % (SE) . | RR . | 95% CI . |
|---|---|---|---|---|---|---|
| Low | 0-1 | 49 | 88.1 (1.1) | 67.3 (2.5) | 1.0 | NA |
| Low-intermediate | 2 | 31 | 70.9 (2.0) | 49.5 (2.8) | 2.2 | 1.8-2.7 |
| High-intermediate | 3 | 15 | 57.4 (3.1) | 27.6 (4.1) | 3.5 | 2.8-4.3 |
| High | 4-5 | 5 | 43.6 (5.6) | 35.8 (5.6) | 4.5 | 3.3-6.2 |
Risk group . | Number of factors* . | Distribution of patients, % . | 5-year OS, % (SE) . | 10-year OS, % (SE) . | RR . | 95% CI . |
|---|---|---|---|---|---|---|
| Low | 0-1 | 49 | 88.1 (1.1) | 67.3 (2.5) | 1.0 | NA |
| Low-intermediate | 2 | 31 | 70.9 (2.0) | 49.5 (2.8) | 2.2 | 1.8-2.7 |
| High-intermediate | 3 | 15 | 57.4 (3.1) | 27.6 (4.1) | 3.5 | 2.8-4.3 |
| High | 4-5 | 5 | 43.6 (5.6) | 35.8 (5.6) | 4.5 | 3.3-6.2 |
OS indicates overall survival; SE, standard error; CI, confidence interval; RR, relative risk (of death); and NA, not applicable.
Factors adversely affecting survival in the IPI2 include performance status greater than 1; number of extra nodal sites greater than 1; serum LDH level greater than the upper limit of normal; Ann Arbor stage III-IV; and age greater than 60 years.