Outcome and relative risk of death according to risk group as defined by the Follicular Lymphoma International Prognostic Index
Risk group . | Number of factors* . | Distribution of patients, % . | 5-year OS, % (SE) . | 10-year OS, % (SE) . | RR . | 95% CI . |
|---|---|---|---|---|---|---|
| Low | 0-1 | 36 | 90.6 (1.2) | 70.7 (2.7) | 1.0 | NA |
| Intermediate | 2 | 37 | 77.6 (1.6) | 50.9 (2.7) | 2.3 | 1.9-2.8 |
| High | ≥ 3 | 27 | 52.5 (2.3) | 35.5 (2.8) | 4.3 | 3.5-5.3 |
Risk group . | Number of factors* . | Distribution of patients, % . | 5-year OS, % (SE) . | 10-year OS, % (SE) . | RR . | 95% CI . |
|---|---|---|---|---|---|---|
| Low | 0-1 | 36 | 90.6 (1.2) | 70.7 (2.7) | 1.0 | NA |
| Intermediate | 2 | 37 | 77.6 (1.6) | 50.9 (2.7) | 2.3 | 1.9-2.8 |
| High | ≥ 3 | 27 | 52.5 (2.3) | 35.5 (2.8) | 4.3 | 3.5-5.3 |
N = 1795. OS indicates overall survival; SE, standard error; CI, confidence interval; RR, relative risk (of death), and NA, not applicable.
Factors adversely affecting survival in the FLIPI include age greater than 60 years; Ann Arbor stage III-IV; number of nodal sites greater than 4; serum LDH level greater than the upper limit of normal; and hemoglobin level less than 120 g/L.