Multivariate OR and their 95% CI for fetal death associated with anti-EPCR levels
Anti-EPCR antibodies and percentile . | Model 1 . | . | . | Model 2 . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| . | Matched OR . | 95% CI . | P . | Matched OR . | 95% CI . | P . | ||||
| IgM | ||||||||||
| 95th | 23.0 | 2.0-266.3 | .012 | 31.0 | 2.0-384.3 | .007 | ||||
| 90th | 7.1 | 1.9-25.6 | .003 | 9.1 | 2.4-34.7 | .001 | ||||
| IgG | ||||||||||
| 95th | 6.8 | 1.2-38.4 | .029 | 11.0 | 1.6-73.5 | .013 | ||||
| 90th | 3.5 | 1.9-11.8 | .040 | 5.5 | 1.5-20.2 | .010 | ||||
| Either IgM or IgG | ||||||||||
| 95th | 10.9 | 2.2-54.7 | .004 | 16.9 | 3-96 | .001 | ||||
| 90th | 6.7 | 2.1-21.2 | .001 | 10.4 | 2.9-37.4 | < .001 | ||||
Anti-EPCR antibodies and percentile . | Model 1 . | . | . | Model 2 . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| . | Matched OR . | 95% CI . | P . | Matched OR . | 95% CI . | P . | ||||
| IgM | ||||||||||
| 95th | 23.0 | 2.0-266.3 | .012 | 31.0 | 2.0-384.3 | .007 | ||||
| 90th | 7.1 | 1.9-25.6 | .003 | 9.1 | 2.4-34.7 | .001 | ||||
| IgG | ||||||||||
| 95th | 6.8 | 1.2-38.4 | .029 | 11.0 | 1.6-73.5 | .013 | ||||
| 90th | 3.5 | 1.9-11.8 | .040 | 5.5 | 1.5-20.2 | .010 | ||||
| Either IgM or IgG | ||||||||||
| 95th | 10.9 | 2.2-54.7 | .004 | 16.9 | 3-96 | .001 | ||||
| 90th | 6.7 | 2.1-21.2 | .001 | 10.4 | 2.9-37.4 | < .001 | ||||
Anti-EPCR autoantibodies were categorized using the 95th and 90th percentiles as cutoff points for the variable in the control group. Model 1 was adjusted for G20210A prothrombin, LACs, aCLs, and, in case of IgM anti-EPCR, for IgG anti-EPCR (vice versa in case of IgG anti-EPCR). Model 2 is like model 1 except that FVL is included for adjustment instead of LACs.