Table 2. PI3K inhibitors suppress... | American Society of Hematology

Table 2.

PI3K inhibitors suppress secretion of proinflammatory cytokines of DCs

	TNF-α, pg/mL	IL-12 p70, pg/mL
Untreated	24 ± 6	49 ± 3
LPS*	1036 ± 161	1831 ± 134
IL-10† + LPS*	156 ± 21	263 ± 43§
LY‡ + LPS*	310 ± 28	402 ± 131∥
Wo‡ + LPS*	284 ± 40	501 ± 16§

	TNF-α, pg/mL	IL-12 p70, pg/mL
Untreated	24 ± 6	49 ± 3
LPS*	1036 ± 161	1831 ± 134
IL-10† + LPS*	156 ± 21	263 ± 43§
LY‡ + LPS*	310 ± 28	402 ± 131∥
Wo‡ + LPS*	284 ± 40	501 ± 16§

Treatment for 48 hours.

Pretreatment for 24 hours.

Pretreatment for 1 hour.

P < .1 compared with LPS.

P < .02 compared with LPS.