Circulating t(11;14)– and t(14;18)–positive cells
. | t(11;14) . | t(14;18) . |
|---|---|---|
| No. of individuals tested | 100 | 86 |
| Median age, y | 37 | 37 |
| Median cell no. tested for each translocation (range) | 7.9×105 (1.6-20.5×105) | 8.3×105 (1.4-29.3×105) |
| No. of translocation-positive individuals (%) | 1 (1) | 39 (45) |
| Median frequency of translocation-positive cells in translocation-positive individuals (range) | 0.6/105 PBMNCs (NA) | 0.2/105 PBMNCs (0.03-2.3/105 PBMNCs) |
. | t(11;14) . | t(14;18) . |
|---|---|---|
| No. of individuals tested | 100 | 86 |
| Median age, y | 37 | 37 |
| Median cell no. tested for each translocation (range) | 7.9×105 (1.6-20.5×105) | 8.3×105 (1.4-29.3×105) |
| No. of translocation-positive individuals (%) | 1 (1) | 39 (45) |
| Median frequency of translocation-positive cells in translocation-positive individuals (range) | 0.6/105 PBMNCs (NA) | 0.2/105 PBMNCs (0.03-2.3/105 PBMNCs) |
Summary of the results obtained by the t(11;14) PCR on peripheral blood samples of 100 healthy individuals and by the t(14;18) PCR on a subgroup of 86 individuals from whom sufficient DNA was available. The number of cells tested was determined by quantitative PCR for k-ras as the reference gene (2 copies per cell).
NA indicates not applicable.