Univariate analysis of cumulative incidence of GvHD and TRM
. | Cumulative incidence, % . | 95% CI for cumulative incidence, % . | P . | Hazard ratio . | 95% CI for hazard ratio . |
|---|---|---|---|---|---|
| GvHD III/IV | |||||
| Wild type | 19 | 13-27 | .001 | 1.0 | |
| Mutated | 44 | 32-60 | 2.7 | (1.5-4.9) | |
| GI GvHD | |||||
| Wild type | 18 | 12-27 | .004 | 1.0 | |
| Mutated | 40 | 28-56 | 2.5 | (1.4-4.7) | |
| 1-year TRM | |||||
| Wild type | 20 | 14-29 | .000 | 1.0 | |
| Mutated | 58 | 45-75 | 2.8 | (1.7-4.9) |
. | Cumulative incidence, % . | 95% CI for cumulative incidence, % . | P . | Hazard ratio . | 95% CI for hazard ratio . |
|---|---|---|---|---|---|
| GvHD III/IV | |||||
| Wild type | 19 | 13-27 | .001 | 1.0 | |
| Mutated | 44 | 32-60 | 2.7 | (1.5-4.9) | |
| GI GvHD | |||||
| Wild type | 18 | 12-27 | .004 | 1.0 | |
| Mutated | 40 | 28-56 | 2.5 | (1.4-4.7) | |
| 1-year TRM | |||||
| Wild type | 20 | 14-29 | .000 | 1.0 | |
| Mutated | 58 | 45-75 | 2.8 | (1.7-4.9) |
The table shows univariate analysis of cumulative incidence of acute GvHD grade III/IV, gastrointestinal (GI) GvHD stage II/IV, and TRM at one year in patient/donor pairs with unmutated NOD2/CARD15 SNPs (wild type, n = 119) versus pairs with either recipient or donor mutations (mutated, n = 50). Cox regression was used to compare groups and analyze hazard ratios. CI indicates confidence interval.