Table 7.

Multivariate analyses of risk factors for overall grade IV toxicity and NRM in both patient groups



Overall grade IV toxicity

Day 100 NRM

1-y NRM
CCI score
OR (95% CI)
P
HR (95% CI)
P
HR (95% CI)
P
0 (n = 93)   Reference    Reference    Reference   
1-2 (n = 30)   2.9 (0.9-9.2)    2.4 (0.8-7.5)    1.6 (0.7-3.8)   
3 or higher (n = 11)
 
5.5 (1.1-29)
 
.06
 
10.5 (1.8-61)
 
.04
 
6.4 (1.6-25)
 
.05
 


Overall grade IV toxicity

Day 100 NRM

1-y NRM
CCI score
OR (95% CI)
P
HR (95% CI)
P
HR (95% CI)
P
0 (n = 93)   Reference    Reference    Reference   
1-2 (n = 30)   2.9 (0.9-9.2)    2.4 (0.8-7.5)    1.6 (0.7-3.8)   
3 or higher (n = 11)
 
5.5 (1.1-29)
 
.06
 
10.5 (1.8-61)
 
.04
 
6.4 (1.6-25)
 
.05
 

Factors included in the analyses were recipient age, donor sex, CMV risk group, disease risk, hematopoietic cell source, prior transplantation and number of prior chemotherapy regimens, and CCI scores.

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