Multivariate analyses of risk factors for overall grade IV toxicity and NRM in both patient groups
. | Overall grade IV toxicity . | . | Day 100 NRM . | . | 1-y NRM . | . | |||
---|---|---|---|---|---|---|---|---|---|
CCI score . | OR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | P . | |||
0 (n = 93) | Reference | Reference | Reference | ||||||
1-2 (n = 30) | 2.9 (0.9-9.2) | 2.4 (0.8-7.5) | 1.6 (0.7-3.8) | ||||||
3 or higher (n = 11) | 5.5 (1.1-29) | .06 | 10.5 (1.8-61) | .04 | 6.4 (1.6-25) | .05 |
. | Overall grade IV toxicity . | . | Day 100 NRM . | . | 1-y NRM . | . | |||
---|---|---|---|---|---|---|---|---|---|
CCI score . | OR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | P . | |||
0 (n = 93) | Reference | Reference | Reference | ||||||
1-2 (n = 30) | 2.9 (0.9-9.2) | 2.4 (0.8-7.5) | 1.6 (0.7-3.8) | ||||||
3 or higher (n = 11) | 5.5 (1.1-29) | .06 | 10.5 (1.8-61) | .04 | 6.4 (1.6-25) | .05 |
Factors included in the analyses were recipient age, donor sex, CMV risk group, disease risk, hematopoietic cell source, prior transplantation and number of prior chemotherapy regimens, and CCI scores.