Table 4.

Neurologic deficits, neuropsychological function, MRI severity, and ALD-Disability Rating Scale (ALD-DRS) levels after hematopoietic cell transplantation in patients with cerebral X-ALD according to baseline performance intelligence quotient (PIQ)




Baseline PIQ below 80

Baseline PIQ of 80 or more

P
Neurologic deficits    .29  
   Median, no. (range)   2 (0-4)   1 (0-4)   
   Observations, no.   32   43   
PIQ    < .01  
   Median (range)   45 (45-63)   78.5 (45-122.5)   
   Observations, no.   6   26   
MRI severity score    .25  
   Median (range)   12.8 (8-19)   8 (0-23.5)   
   Observations, no.   8   23   
ALD-DRS level    < .01  
   Median (range)   IV (I-IV)   II (0-IV)   
   Observations, no.
 
28
 
36
 

 



Baseline PIQ below 80

Baseline PIQ of 80 or more

P
Neurologic deficits    .29  
   Median, no. (range)   2 (0-4)   1 (0-4)   
   Observations, no.   32   43   
PIQ    < .01  
   Median (range)   45 (45-63)   78.5 (45-122.5)   
   Observations, no.   6   26   
MRI severity score    .25  
   Median (range)   12.8 (8-19)   8 (0-23.5)   
   Observations, no.   8   23   
ALD-DRS level    < .01  
   Median (range)   IV (I-IV)   II (0-IV)   
   Observations, no.
 
28
 
36
 

 
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