Table 2. Cytokine production by... | American Society of Hematology

Table 2.

Cytokine production by CD40L-activated BCP-ALL cells

Patient	IL-12p40, pg/mL	IL-12p70, pg/mL	IL-10, pg/mL
1	100	< 26	540
2	12900	< 26	< 62
3	ND	< 26	< 62
4	2140	< 26	160
5	ND	< 26	250
6	250	< 26	160
7	< 16	< 26	230
8	6650	< 26	210
9	< 16	< 26	240
10	2100	< 26	< 62
11	180	< 26	200
12	200	< 26	390
13	< 16	< 26	< 62
14	360	< 26	< 62
15	180	< 26	210
16	210	< 26	150
17	660	< 26	150
18	760	< 26	750
19	ND	< 26	485
DCs	ND	5000 ± 1000	2000 ± 500

Patient	IL-12p40, pg/mL	IL-12p70, pg/mL	IL-10, pg/mL
1	100	< 26	540
2	12900	< 26	< 62
3	ND	< 26	< 62
4	2140	< 26	160
5	ND	< 26	250
6	250	< 26	160
7	< 16	< 26	230
8	6650	< 26	210
9	< 16	< 26	240
10	2100	< 26	< 62
11	180	< 26	200
12	200	< 26	390
13	< 16	< 26	< 62
14	360	< 26	< 62
15	180	< 26	210
16	210	< 26	150
17	660	< 26	150
18	760	< 26	750
19	ND	< 26	485
DCs	ND	5000 ± 1000	2000 ± 500

BCP-ALL cells cultured on HBMS were incubated (10⁶/mL) with or without a CD40L-transfected cell line for 48 hours. Cytokines were measured using ELISA in the supernatants. Normal DCs were differentiated from monocytes in the presence of GM-CSF + IL-13.

ND indicates not determined.

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