Table 6.

Side effects according to treatment arms


Effects

CHOP-21, %

CHOP-14, %

CHOEP-21, %

CHOEP-14, %

P
Leukocytopenia   34.1   33.6   73.6   72.5   < .001  
Thrombocytopenia   2.4   1.2   7.0   22.2   < .001  
Anemia   3.6   5.6   8.5   35.4   < .001  
Infection   1.8   4.2   4.4   5.2   .390  
Mucositis   2.9   3.0   1.6   6.9   .048  
Cardiac toxicity   0.6   0.6   2.8   0.6   .232  
Neurologic toxicity   3.5   0.6   1.6   3.5   .171  
Renal toxicity   0.0   0.0   0.0   1.2   .182  
Lung toxicity   0.0   0.6   1.7   1.7   .320  
Nausea or vomiting   11.7   6.5   9.4   8.6   .415  
Alopecia
 
63.6
 
64.8
 
70.9
 
67.6
 
.469
 

Effects

CHOP-21, %

CHOP-14, %

CHOEP-21, %

CHOEP-14, %

P
Leukocytopenia   34.1   33.6   73.6   72.5   < .001  
Thrombocytopenia   2.4   1.2   7.0   22.2   < .001  
Anemia   3.6   5.6   8.5   35.4   < .001  
Infection   1.8   4.2   4.4   5.2   .390  
Mucositis   2.9   3.0   1.6   6.9   .048  
Cardiac toxicity   0.6   0.6   2.8   0.6   .232  
Neurologic toxicity   3.5   0.6   1.6   3.5   .171  
Renal toxicity   0.0   0.0   0.0   1.2   .182  
Lung toxicity   0.0   0.6   1.7   1.7   .320  
Nausea or vomiting   11.7   6.5   9.4   8.6   .415  
Alopecia
 
63.6
 
64.8
 
70.9
 
67.6
 
.469
 

Values in the table represent the percentage of all patients experiencing the respective side effect at least once.