Expression of angiogenic cytokines and their receptors by immunohistochemistry
. | No. patients (%) . | . | . | . | ||
|---|---|---|---|---|---|---|
| Cytokine/cytokine receptor . | MGUS n = 15 . | SMM n = 23 . | NMM n = 19 . | Level of expression . | ||
| VEGF | 7 (47) | 11 (48) | 7 (37) | −/+ | ||
| 8 (53) | 12 (52) | 12 (63) | ++/+++ | |||
| bFGF | 8 (54) | 13 (57) | 8 (42) | −/+ | ||
| 7 (46) | 10 (43) | 11 (58) | ++/+++ | |||
| VEGFR1 | 8 (54) | 10 (44) | 5 (26) | −/+ | ||
| 7 (46) | 13 (56) | 14 (74) | ++/+++ | |||
| VEGFR2 | 7 (47) | 13 (57) | 8 (42) | −/+ | ||
| 8 (53) | 10 (43) | 11 (58) | ++/+++ | |||
| FGFR3 | 7 (46) | 14 (61) | 9 (48) | −/+ | ||
| 8 (54) | 9 (39) | 10 (52) | ++/+++ | |||
| FGFR2 | 7 (47) | 12 (52) | 8 (42) | −/+ | ||
| 8 (54) | 11 (48) | 11 (58) | ++/+++ | |||
. | No. patients (%) . | . | . | . | ||
|---|---|---|---|---|---|---|
| Cytokine/cytokine receptor . | MGUS n = 15 . | SMM n = 23 . | NMM n = 19 . | Level of expression . | ||
| VEGF | 7 (47) | 11 (48) | 7 (37) | −/+ | ||
| 8 (53) | 12 (52) | 12 (63) | ++/+++ | |||
| bFGF | 8 (54) | 13 (57) | 8 (42) | −/+ | ||
| 7 (46) | 10 (43) | 11 (58) | ++/+++ | |||
| VEGFR1 | 8 (54) | 10 (44) | 5 (26) | −/+ | ||
| 7 (46) | 13 (56) | 14 (74) | ++/+++ | |||
| VEGFR2 | 7 (47) | 13 (57) | 8 (42) | −/+ | ||
| 8 (53) | 10 (43) | 11 (58) | ++/+++ | |||
| FGFR3 | 7 (46) | 14 (61) | 9 (48) | −/+ | ||
| 8 (54) | 9 (39) | 10 (52) | ++/+++ | |||
| FGFR2 | 7 (47) | 12 (52) | 8 (42) | −/+ | ||
| 8 (54) | 11 (48) | 11 (58) | ++/+++ | |||