Frequency of CD8+ T cells in PBMCs from healthy seropositive donors that produce IFNγ after stimulation with autologous AD169-infected fibroblasts or pp65 peptides
. | Mean % CD8+ T cells responding to stimulus with* . | . | . | . | |||
|---|---|---|---|---|---|---|---|
| Donor no. (HLA type) . | AD169-infected fibroblasts . | pp65495-503, HLA-A2 . | pp65417-426, HLA-B7 . | pp65265-274, HLA-B7 . | |||
| 1 (A3/B7, 35) | 2.96 | ND | 0.99 | 2.05 | |||
| 2 (A2, 11/B7, 18) | 1.06 | 0.17 | 0.18 | 0.60 | |||
| 3 (A2, 3/B40, 44) | 1.42 | 1.51 | ND | ND | |||
| 4 (A2, 26/B13, 40) | 0.60 | 0.40 | ND | ND | |||
| 5 (A2, 11/B14, 44) | 0.35 | 0.19 | ND | ND | |||
| 6 (A2, 25/B7, 27) | 0.23 | 0.06 | 0 | 0.50 | |||
| 7 (A2/B51) | 2.20 | 2.62 | ND | ND | |||
| 8 (A1, 3/B7, 57) | 0.56 | ND | 0.50 | 0.15 | |||
| 9 (A2, 22/B8, 18) | 0.60 | 0.96 | ND | ND | |||
| 10 (A2, 3/B7, 51) | 0.91 | 0.18 | 0.43 | 0.70 | |||
. | Mean % CD8+ T cells responding to stimulus with* . | . | . | . | |||
|---|---|---|---|---|---|---|---|
| Donor no. (HLA type) . | AD169-infected fibroblasts . | pp65495-503, HLA-A2 . | pp65417-426, HLA-B7 . | pp65265-274, HLA-B7 . | |||
| 1 (A3/B7, 35) | 2.96 | ND | 0.99 | 2.05 | |||
| 2 (A2, 11/B7, 18) | 1.06 | 0.17 | 0.18 | 0.60 | |||
| 3 (A2, 3/B40, 44) | 1.42 | 1.51 | ND | ND | |||
| 4 (A2, 26/B13, 40) | 0.60 | 0.40 | ND | ND | |||
| 5 (A2, 11/B14, 44) | 0.35 | 0.19 | ND | ND | |||
| 6 (A2, 25/B7, 27) | 0.23 | 0.06 | 0 | 0.50 | |||
| 7 (A2/B51) | 2.20 | 2.62 | ND | ND | |||
| 8 (A1, 3/B7, 57) | 0.56 | ND | 0.50 | 0.15 | |||
| 9 (A2, 22/B8, 18) | 0.60 | 0.96 | ND | ND | |||
| 10 (A2, 3/B7, 51) | 0.91 | 0.18 | 0.43 | 0.70 | |||
ND indicates not determined.
Data represent the mean of at least 2 experiments per donor.