Consensus regions in 53 patients with MCL
Chromosomal band . | Minimal segment of genomic gain/loss, Mbp . | Approximate size, Mbp . | No. of cases . | Candidate genes . |
|---|---|---|---|---|
| –8p21 | 20.7-23.1 | 2.4 | 18 | TNFRSF10B |
| –9p21-9p22 | 14.3-26.5 | 12.2 | 19 | CDKN2A, CDKN2B |
| –10p14-10p15 | 0.0-12.4 | 12.4 | 11 | — |
| +10p13 | 22.1-24.8 | 2.7 | 6 | BMI1 |
| +11q13 | 63.9-65.3 | 1.4 | 6 | RELA, MAP4K2 |
| +11q13 | 66.5-71.7 | 5.2 | 6 | CCND1, FGF3, FGF4 |
| –11q22-11q23 | 108.0-109.7 | 1.7 | 23 | ATM, DDX10 |
| +11q23 | 115.9-123.0 | 7.1 | 4 | MLL |
| –12p11-12p13 | 10.2-21.8 | 11.6 | 9 | CDKN1B |
| –13q14 | 48.1-48.5 | 0.4 | 29 | RFP2, BCMSUN |
| –13q33-13q34 | 102.2-109.1 | 6.9 | 26 | — |
| +18q21 | 55.3-64.6 | 9.3 | 8 | BCL2 |
Chromosomal band . | Minimal segment of genomic gain/loss, Mbp . | Approximate size, Mbp . | No. of cases . | Candidate genes . |
|---|---|---|---|---|
| –8p21 | 20.7-23.1 | 2.4 | 18 | TNFRSF10B |
| –9p21-9p22 | 14.3-26.5 | 12.2 | 19 | CDKN2A, CDKN2B |
| –10p14-10p15 | 0.0-12.4 | 12.4 | 11 | — |
| +10p13 | 22.1-24.8 | 2.7 | 6 | BMI1 |
| +11q13 | 63.9-65.3 | 1.4 | 6 | RELA, MAP4K2 |
| +11q13 | 66.5-71.7 | 5.2 | 6 | CCND1, FGF3, FGF4 |
| –11q22-11q23 | 108.0-109.7 | 1.7 | 23 | ATM, DDX10 |
| +11q23 | 115.9-123.0 | 7.1 | 4 | MLL |
| –12p11-12p13 | 10.2-21.8 | 11.6 | 9 | CDKN1B |
| –13q14 | 48.1-48.5 | 0.4 | 29 | RFP2, BCMSUN |
| –13q33-13q34 | 102.2-109.1 | 6.9 | 26 | — |
| +18q21 | 55.3-64.6 | 9.3 | 8 | BCL2 |
The genomic localization information is according to the NCBI database.—indicates not applicable.