Table 1.

Characteristics of patients treated with FAI or FM


Characteristics

FAI

FM

P
No. patients   32   62   
Average age, y (range)   61 (27-74)   54 (22-75)   .001  
No. female (%)/no. male (%)   18 (56)/14 (44)   29 (47)/33 (53)   .514  
Average mos. from diagnosis to treatment (range)   10 (1.1-48.6)   12 (0.9-173.6)   .662  
No. prior therapies (range)   2 (0-4)   2 (0-8)   .399  
Diagnosis, no. (%)    
   AML   26 (81)   42 (68)   
   MDS   6 (19)   20 (32)   .253  
Stage at transplantation, no. (%)    
   Remission   14 (44)   10 (16)   .006  
   Not in remission   18 (56)   52 (84)   
First remission at transplantation, no. (%)   9 (28)   2 (3)   .0008  
Donor type, no. (%)    
   Matched sibling   26 (81)   25 (40)   
   Mismatched related   6 (19)   8 (13)   <.001  
   Matched unrelated   0 (0)   29 (47)   
Stem cell source, no. (%)    
   Bone marrow   27 (84)   26 (42)   <.001  
   Peripheral blood
 
5 (16)
 
36 (58)
 

 

Characteristics

FAI

FM

P
No. patients   32   62   
Average age, y (range)   61 (27-74)   54 (22-75)   .001  
No. female (%)/no. male (%)   18 (56)/14 (44)   29 (47)/33 (53)   .514  
Average mos. from diagnosis to treatment (range)   10 (1.1-48.6)   12 (0.9-173.6)   .662  
No. prior therapies (range)   2 (0-4)   2 (0-8)   .399  
Diagnosis, no. (%)    
   AML   26 (81)   42 (68)   
   MDS   6 (19)   20 (32)   .253  
Stage at transplantation, no. (%)    
   Remission   14 (44)   10 (16)   .006  
   Not in remission   18 (56)   52 (84)   
First remission at transplantation, no. (%)   9 (28)   2 (3)   .0008  
Donor type, no. (%)    
   Matched sibling   26 (81)   25 (40)   
   Mismatched related   6 (19)   8 (13)   <.001  
   Matched unrelated   0 (0)   29 (47)   
Stem cell source, no. (%)    
   Bone marrow   27 (84)   26 (42)   <.001  
   Peripheral blood
 
5 (16)
 
36 (58)
 

 

FAI indicates fludarabine, araC, and idarubicin; FM, fludarabine and melphalan.

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