Summary of outcomes
Patient no. . | Donor . | Age, y . | Time to GVHD, d . | Skin stage . | Gl stage . | Liver stage . | Days to infliximab* . | Response to infliximab . | Death . | Cause . | Days to last follow-up† . |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | 1 Ag MM rel | 37 | 28 | 3 | 0 | 0 | 41 | CR | Yes | GVHD | 83 |
2 | 1 Ag MM rel | 62 | 41 | 1 | 1 | 0 | 53 | CR | Yes | Relapse | 165 |
3 | HLA unrel | 25 | 8 | 3 | 0 | 0 | 48 | CR | No | — | 682 |
4 | HLA unrel | 60 | 11 | 2 | 0 | 0 | 31 | CR | No | — | 298 |
5 | HLA unrel | 36 | 12 | 3 | 0 | 0 | 42 | PR | Yes | GVHD | 120 |
6 | HLA unrel | 45 | 16 | 0 | 1 | 0 | 7 | PD | Yes | GVHD | 178 |
7 | HLA unrel | 64 | 20 | 0 | 1 | 0 | 11 | CR | No | — | 640 |
8 | HLA unrel | 19 | 32 | 3 | 0 | 0 | 7 | NR | Yes | Relapse | 115 |
9 | HLA unrel | 62 | 36 | 0 | 3 | 0 | 37 | CR | Yes | GVHD | 19 |
10 | HLA unrel | 45 | 40 | 1 | 1 | 0 | 14 | CR | No | — | 806 |
11 | HLA sib | 55 | 18 | 1 | 0 | 0 | 45 | NR | Yes | GVHD | 50 |
12 | HLA sib | 62 | 19 | 0 | 2 | 0 | 18 | NR | Yes | Pneumonia | 231 |
13 | HLA sib | 63 | 20 | 0 | 1 | 0 | 5 | CR | Yes | GVHD | 257 |
14 | HLA sib | 40 | 23 | 0 | 0 | 1 | 41 | CR | Yes | GVHD | 144 |
15 | HLA sib | 47 | 30 | 0 | 3 | 1 | 4 | PD | Yes | GVHD | 99 |
16 | HLA sib | 27 | 31 | 0 | 4 | 0 | 6 | CR | No | — | 352 |
17 | HLA sib | 53 | 34 | 1 | 0 | 0 | 59 | CR | No | — | 390 |
18 | HLA sib | 53 | 40 | 0 | 1 | 0 | 7 | CR | No | — | 588 |
19 | HLA sib | 55 | 57 | 0 | 1 | 0 | 27 | CR | Yes | GVHD | 130 |
20 | HLA sib | 47 | 91 | 0 | 1 | 0 | 4 | NR | No | — | 861 |
21 | HLA sib | 29 | 122‡ | 0 | 0 | 1 | 47 | NR | Yes | Relapse | 161 |
Patient no. . | Donor . | Age, y . | Time to GVHD, d . | Skin stage . | Gl stage . | Liver stage . | Days to infliximab* . | Response to infliximab . | Death . | Cause . | Days to last follow-up† . |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | 1 Ag MM rel | 37 | 28 | 3 | 0 | 0 | 41 | CR | Yes | GVHD | 83 |
2 | 1 Ag MM rel | 62 | 41 | 1 | 1 | 0 | 53 | CR | Yes | Relapse | 165 |
3 | HLA unrel | 25 | 8 | 3 | 0 | 0 | 48 | CR | No | — | 682 |
4 | HLA unrel | 60 | 11 | 2 | 0 | 0 | 31 | CR | No | — | 298 |
5 | HLA unrel | 36 | 12 | 3 | 0 | 0 | 42 | PR | Yes | GVHD | 120 |
6 | HLA unrel | 45 | 16 | 0 | 1 | 0 | 7 | PD | Yes | GVHD | 178 |
7 | HLA unrel | 64 | 20 | 0 | 1 | 0 | 11 | CR | No | — | 640 |
8 | HLA unrel | 19 | 32 | 3 | 0 | 0 | 7 | NR | Yes | Relapse | 115 |
9 | HLA unrel | 62 | 36 | 0 | 3 | 0 | 37 | CR | Yes | GVHD | 19 |
10 | HLA unrel | 45 | 40 | 1 | 1 | 0 | 14 | CR | No | — | 806 |
11 | HLA sib | 55 | 18 | 1 | 0 | 0 | 45 | NR | Yes | GVHD | 50 |
12 | HLA sib | 62 | 19 | 0 | 2 | 0 | 18 | NR | Yes | Pneumonia | 231 |
13 | HLA sib | 63 | 20 | 0 | 1 | 0 | 5 | CR | Yes | GVHD | 257 |
14 | HLA sib | 40 | 23 | 0 | 0 | 1 | 41 | CR | Yes | GVHD | 144 |
15 | HLA sib | 47 | 30 | 0 | 3 | 1 | 4 | PD | Yes | GVHD | 99 |
16 | HLA sib | 27 | 31 | 0 | 4 | 0 | 6 | CR | No | — | 352 |
17 | HLA sib | 53 | 34 | 1 | 0 | 0 | 59 | CR | No | — | 390 |
18 | HLA sib | 53 | 40 | 0 | 1 | 0 | 7 | CR | No | — | 588 |
19 | HLA sib | 55 | 57 | 0 | 1 | 0 | 27 | CR | Yes | GVHD | 130 |
20 | HLA sib | 47 | 91 | 0 | 1 | 0 | 4 | NR | No | — | 861 |
21 | HLA sib | 29 | 122‡ | 0 | 0 | 1 | 47 | NR | Yes | Relapse | 161 |
1 Ag MM rel indicates 1 antigen-mismatched, related; HLA sib, HLA-matched sibling; and HLA unrel, HLA-matched, unrelated.
Days from diagnosis of GVHD to infliximab.
Days from initiation of infliximab to last follow-up.
Patient received a donor lymphocyte infusion 20 days before clinical manifestations of acute GVHD.