Sources of stem cells, engraftment, and chimerism
Characteristic . | Value . |
|---|---|
| Source of stem cells, n (%) | |
| Peripheral blood | 49 (51) |
| Bone marrow | 47 (49) |
| CD34+ cells | |
| No. of patients evaluated | 84 |
| Median no. CD34+ cells infused, × 106/kg (range) | 4.6 (0.24-9.2) |
| CD3+ cells | |
| No. of patients evaluated | 81 |
| Median no. CD3+ cells infused, × 106/kg (range) | 87.2 (8.2-366) |
| ANC | |
| No. of patients evaluated | 95 |
| Median time to ANC greater than 0.5 × 109/L, d (range, d) | 12 (9-25) |
| Platelets | |
| Platelet count greater than 20 × 109/L | |
| No. of patients evaluated | 89 |
| Median time to platelet count greater than 20 × 109/L, d (range, d) | 13 (0-125) |
| Platelet count greater than 50 × 109/L | |
| No. of patients evaluated | 82 |
| Median time to platelet count greater than 50 × 109/L, d (range, d) | 18 (10-134) |
| Platelet count greater than 100 × 109/L | |
| No. of patients evaluated | 64 |
| Median time to platelet count greater than 100 × 109/L, d (range, d) | 22 (12-89) |
| Chimerism, median % of donor cells (range) | |
| Transplant d 100 | |
| T lymphocyte; n = 55 | 100 (51-100) |
| Myeloid; n = 52 | 100 (80-100) |
| Transplant d 180 | |
| T lymphocyte; n = 22 | 100 (90-100) |
| Myeloid; n = 23 | 100 (88-100) |
Characteristic . | Value . |
|---|---|
| Source of stem cells, n (%) | |
| Peripheral blood | 49 (51) |
| Bone marrow | 47 (49) |
| CD34+ cells | |
| No. of patients evaluated | 84 |
| Median no. CD34+ cells infused, × 106/kg (range) | 4.6 (0.24-9.2) |
| CD3+ cells | |
| No. of patients evaluated | 81 |
| Median no. CD3+ cells infused, × 106/kg (range) | 87.2 (8.2-366) |
| ANC | |
| No. of patients evaluated | 95 |
| Median time to ANC greater than 0.5 × 109/L, d (range, d) | 12 (9-25) |
| Platelets | |
| Platelet count greater than 20 × 109/L | |
| No. of patients evaluated | 89 |
| Median time to platelet count greater than 20 × 109/L, d (range, d) | 13 (0-125) |
| Platelet count greater than 50 × 109/L | |
| No. of patients evaluated | 82 |
| Median time to platelet count greater than 50 × 109/L, d (range, d) | 18 (10-134) |
| Platelet count greater than 100 × 109/L | |
| No. of patients evaluated | 64 |
| Median time to platelet count greater than 100 × 109/L, d (range, d) | 22 (12-89) |
| Chimerism, median % of donor cells (range) | |
| Transplant d 100 | |
| T lymphocyte; n = 55 | 100 (51-100) |
| Myeloid; n = 52 | 100 (80-100) |
| Transplant d 180 | |
| T lymphocyte; n = 22 | 100 (90-100) |
| Myeloid; n = 23 | 100 (88-100) |