CD4 TREC contents in 3 subgroups of HIV-1-infected subjects identified by number of CD4 TRECs compared with HIV-negative subjects
Age and HIV-1-infected subject group* . | HIV-negative subjects . | . | More than 500 CD4 T cells . | . | . | 200 to 500 CD4 T cells . | . | . | Fewer than 200 CD4 T cells . | . | . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | N . | CD4 TRECs, mean ± 3 × SE . | N . | CD4 TRECs . | P . | N . | CD4 TRECs . | P . | N . | CD4 TRECs . | P . | |||||||
| 20-44 y | 68 | 11 553 ± 3240 | ||||||||||||||||
| Higher | 34 | 30 615 ± 2394 | < .001† | 27 | 25 541 ± 220 | < .001† | 3 | 24 487 ± 8757 | .019† | |||||||||
| Similar to | 14 | 11 055 ± 525 | .680 | 18 | 10 549 ± 474 | .397 | 5 | 11 790 ± 867 | .953 | |||||||||
| Lower | 19 | 3634 ± 599 | < .001† | 37 | 4216 ± 398 | < .001† | 26 | 3802 ± 581 | < .001† | |||||||||
| 45-59 y | 34 | 6750 ± 2481 | ||||||||||||||||
| Higher | 8 | 19 550 ± 2849 | .002† | 6 | 15 143 ± 1760 | < .001† | NA | NA | NA | |||||||||
| Similar to | 8 | 5760 ± 236 | .257 | 4 | 5550 ± 492 | .224 | NA | NA | NA | |||||||||
| Lower | 16 | 1896 ± 351 | < .001† | 10 | 791 ± 308 | < .001† | NA | NA | NA | |||||||||
Age and HIV-1-infected subject group* . | HIV-negative subjects . | . | More than 500 CD4 T cells . | . | . | 200 to 500 CD4 T cells . | . | . | Fewer than 200 CD4 T cells . | . | . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | N . | CD4 TRECs, mean ± 3 × SE . | N . | CD4 TRECs . | P . | N . | CD4 TRECs . | P . | N . | CD4 TRECs . | P . | |||||||
| 20-44 y | 68 | 11 553 ± 3240 | ||||||||||||||||
| Higher | 34 | 30 615 ± 2394 | < .001† | 27 | 25 541 ± 220 | < .001† | 3 | 24 487 ± 8757 | .019† | |||||||||
| Similar to | 14 | 11 055 ± 525 | .680 | 18 | 10 549 ± 474 | .397 | 5 | 11 790 ± 867 | .953 | |||||||||
| Lower | 19 | 3634 ± 599 | < .001† | 37 | 4216 ± 398 | < .001† | 26 | 3802 ± 581 | < .001† | |||||||||
| 45-59 y | 34 | 6750 ± 2481 | ||||||||||||||||
| Higher | 8 | 19 550 ± 2849 | .002† | 6 | 15 143 ± 1760 | < .001† | NA | NA | NA | |||||||||
| Similar to | 8 | 5760 ± 236 | .257 | 4 | 5550 ± 492 | .224 | NA | NA | NA | |||||||||
| Lower | 16 | 1896 ± 351 | < .001† | 10 | 791 ± 308 | < .001† | NA | NA | NA | |||||||||
P values represent t test comparisons between values in both groups. NA indicates not applicable.
HIV-1-infected subjects are divided by age (in years) and subdivided according to whether their TREC counts were higher, similar to, or lower than those of their HIV-negative counterparts.
Statistically significant values.