Clinical and hematologic characteristics of patients
Characteristic . | Value . |
|---|---|
| Total no. of patients | 90 |
| Age, y | |
| Median | 44 |
| Range | 16-88 |
| 60 y or younger, n | 72 |
| Sex, n | |
| Male | 44 |
| Female | 46 |
| WBC count, 109/L | |
| Median | 58 |
| Range | 1-319 |
| FAB class | |
| M0 | 3 |
| M1 | 18 |
| M2 | 19 |
| M3 | 5 |
| M4 | 23 |
| M5 | 22 |
| Cytogenetic abnormality* | |
| Favorable | 14 |
| Intermediate | 69 |
| Unfavorable | 7 |
| Initial therapy response | |
| CR | 62 |
| No CR | 28 |
Characteristic . | Value . |
|---|---|
| Total no. of patients | 90 |
| Age, y | |
| Median | 44 |
| Range | 16-88 |
| 60 y or younger, n | 72 |
| Sex, n | |
| Male | 44 |
| Female | 46 |
| WBC count, 109/L | |
| Median | 58 |
| Range | 1-319 |
| FAB class | |
| M0 | 3 |
| M1 | 18 |
| M2 | 19 |
| M3 | 5 |
| M4 | 23 |
| M5 | 22 |
| Cytogenetic abnormality* | |
| Favorable | 14 |
| Intermediate | 69 |
| Unfavorable | 7 |
| Initial therapy response | |
| CR | 62 |
| No CR | 28 |
WBC indicates white blood cell.
Favorable cytogenetic abnormalities included t(8;21), t(15;17), or inv(16); unfavorable cytogenetic abnormalities included del(5), Del(7), deletions of the long arms of chromosomes 5 or 7 (5q-, 7q-), t(6;9), 11q23 abnormalities, and complex karyotypes (> 3 abnormalities). Other karyotypic aberrations and normal karyotypes were included in the intermediate prognostic category.