FACT-An scale scores at baseline and during follow-up
. | Week 0 . | . | Week 12 . | . | Week 28 . | . | Week 52 . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | A . | B . | A . | B . | A . | B . | A . | B . | ||||
| FACT-An total score, mean | 115.6 | 112.5 | 111.8 | 114.4 | 123.1 | 118.3 | 107.1 | 105.4 | ||||
| Total anemia subscale score, mean | 46.4 | 46.1 | 50.7 | 48.3 | 55.5 | 47.1 | 45.6 | 42.1 | ||||
| Total fatigue subscale score, mean | 29 | 28.3 | 31.7 | 29.2 | 36.9 | 28.3 | 28.4 | 23.6 | ||||
| Subjects with clinical improvement in Fact-An total score, n (%) | — | — | 6 (33) | 10 (43)* | 7 (46.7) | 12 (62)* | 3 (25) | 3 (17)* | ||||
| Subjects with clinical improvement on anemia subscale, n (%) | — | — | 5 (28) | 7 (30)* | 8 (53) | 6 (32)* | 3 (25) | 2 (11)* | ||||
| Subjects with clinical improvement on fatigue subscale, n (%) | — | — | 6 (33) | 9 (39)* | 8 (53) | 5 (26)* | 3 (25) | 2 (11)* | ||||
| Responses, n completion rate (%) | 29 (97) | 28 (93) | 19 (79) | 23 (85) | 15 (68) | 18 (72) | 10 (50) | 16 (67) | ||||
. | Week 0 . | . | Week 12 . | . | Week 28 . | . | Week 52 . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | A . | B . | A . | B . | A . | B . | A . | B . | ||||
| FACT-An total score, mean | 115.6 | 112.5 | 111.8 | 114.4 | 123.1 | 118.3 | 107.1 | 105.4 | ||||
| Total anemia subscale score, mean | 46.4 | 46.1 | 50.7 | 48.3 | 55.5 | 47.1 | 45.6 | 42.1 | ||||
| Total fatigue subscale score, mean | 29 | 28.3 | 31.7 | 29.2 | 36.9 | 28.3 | 28.4 | 23.6 | ||||
| Subjects with clinical improvement in Fact-An total score, n (%) | — | — | 6 (33) | 10 (43)* | 7 (46.7) | 12 (62)* | 3 (25) | 3 (17)* | ||||
| Subjects with clinical improvement on anemia subscale, n (%) | — | — | 5 (28) | 7 (30)* | 8 (53) | 6 (32)* | 3 (25) | 2 (11)* | ||||
| Subjects with clinical improvement on fatigue subscale, n (%) | — | — | 6 (33) | 9 (39)* | 8 (53) | 5 (26)* | 3 (25) | 2 (11)* | ||||
| Responses, n completion rate (%) | 29 (97) | 28 (93) | 19 (79) | 23 (85) | 15 (68) | 18 (72) | 10 (50) | 16 (67) | ||||
—indicates not applicable.
P > .2 (Fisher exact test).