Flow cytometry analysis of CC and CXC receptors in B-cell CLDs
Cell types . | CCR1 . | CCR2 . | CCR3 . | CCR5 . | CCR6 . | CXCR1 . | CXCR2 . | CXCR3 . | CXCR4 . | CXCR5 . |
|---|---|---|---|---|---|---|---|---|---|---|
| CLL | 4.9 ± 2.1 | 4.4 ± 2.1 | 27.1 ± 7.7 | 0.9 ± 0.3 | 21.5 ± 5.3 | 1.5 ± 0.4 | 0.2 ± 0.1 | 32.6 ± 0.7 | 244.5 ± 55.3 | 70.2 ± 7.6 |
| HCL | 51.8 ± 33.4 | 30.0 ± 9.4 | 183.8 ± 57.4 | 6.0 ± 1.5 | 118.2 ± 30.1 | 4.2 ± 0.7 | 0.7 ± 0.2 | 12.1 ± 3.6 | 210.9 ± 39.5 | 87.1 ± 22.2 |
| MCL | 1.4 ± 1.1 | 13.1 ± 7.5 | 83.7 ± 54.9 | 4.0 ± 1.3 | 67.8 ± 13.8 | 2.4 ± 1.0 | 1.1 ± 0.3 | 23.9 ± 1.4 | 223.9 ± 62.2 | 71.7 ± 23.9 |
| MZL | 0.7 ± 0.4 | 1.6 ± 1.5 | 1.1 ± 0.5 | 3.8 ± 1.5 | 64.6 ± 25.3 | 3.3 ± 1.8 | 1.6 ± 0.9 | 35.9 ± 4.2 | 94.5 ± 41.6 | 34.2 ± 11.7 |
| SLL | 1.1 ± 0.7 | 3.3 ± 2.5 | 18.6 ± 17.2 | 1.6 ± 0.5 | 25.8 ± 7.6 | 2.0 ± 0.3 | 1.1 ± 0.2 | 8.1 ± 1.7 | 86.9 ± 19.8 | 17.8 ± 9.8 |
| FCL | 1.6 ± 0.7 | 3.0 ± 0.9 | 0.76 ± 0.6 | 8.1 ± 3.8 | 1.3 ± 1.6 | 2.2 ± 1.3 | 0.4 ± 0.2 | 5.7 ± 4.2 | 131.7 ± 58.9 | 60.2 ± 16.9 |
| Normal B cells | 5.1 ± 2.2 | 6.4 ± 4.7 | 28.1 ± 6.3 | 2.2 ± 1.2 | 30.7 ± 9.5 | 4.4 ± 1.7 | 0.6 ± 0.2 | 5.6 ± 2.2 | 290.6 ± 85.5 | 54.4 ± 19.5 |
Cell types . | CCR1 . | CCR2 . | CCR3 . | CCR5 . | CCR6 . | CXCR1 . | CXCR2 . | CXCR3 . | CXCR4 . | CXCR5 . |
|---|---|---|---|---|---|---|---|---|---|---|
| CLL | 4.9 ± 2.1 | 4.4 ± 2.1 | 27.1 ± 7.7 | 0.9 ± 0.3 | 21.5 ± 5.3 | 1.5 ± 0.4 | 0.2 ± 0.1 | 32.6 ± 0.7 | 244.5 ± 55.3 | 70.2 ± 7.6 |
| HCL | 51.8 ± 33.4 | 30.0 ± 9.4 | 183.8 ± 57.4 | 6.0 ± 1.5 | 118.2 ± 30.1 | 4.2 ± 0.7 | 0.7 ± 0.2 | 12.1 ± 3.6 | 210.9 ± 39.5 | 87.1 ± 22.2 |
| MCL | 1.4 ± 1.1 | 13.1 ± 7.5 | 83.7 ± 54.9 | 4.0 ± 1.3 | 67.8 ± 13.8 | 2.4 ± 1.0 | 1.1 ± 0.3 | 23.9 ± 1.4 | 223.9 ± 62.2 | 71.7 ± 23.9 |
| MZL | 0.7 ± 0.4 | 1.6 ± 1.5 | 1.1 ± 0.5 | 3.8 ± 1.5 | 64.6 ± 25.3 | 3.3 ± 1.8 | 1.6 ± 0.9 | 35.9 ± 4.2 | 94.5 ± 41.6 | 34.2 ± 11.7 |
| SLL | 1.1 ± 0.7 | 3.3 ± 2.5 | 18.6 ± 17.2 | 1.6 ± 0.5 | 25.8 ± 7.6 | 2.0 ± 0.3 | 1.1 ± 0.2 | 8.1 ± 1.7 | 86.9 ± 19.8 | 17.8 ± 9.8 |
| FCL | 1.6 ± 0.7 | 3.0 ± 0.9 | 0.76 ± 0.6 | 8.1 ± 3.8 | 1.3 ± 1.6 | 2.2 ± 1.3 | 0.4 ± 0.2 | 5.7 ± 4.2 | 131.7 ± 58.9 | 60.2 ± 16.9 |
| Normal B cells | 5.1 ± 2.2 | 6.4 ± 4.7 | 28.1 ± 6.3 | 2.2 ± 1.2 | 30.7 ± 9.5 | 4.4 ± 1.7 | 0.6 ± 0.2 | 5.6 ± 2.2 | 290.6 ± 85.5 | 54.4 ± 19.5 |
Data are reported as mean ± SE of the MFI values for each group of subjects after subtracting the MFI of isotype control mAb from the MFI of positively stained samples.