Quantitation of the dose-dependent effect of JNKDN on the transcription driven by the uPA-MP LNCaP cells cotransfected with MEKK (400 ng) or MEK1 (400 ng)
Constructs . | Fold decrease . |
|---|---|
| uPA-MP + MEKK | 1 |
| uPA-MP + MEKK + 4 ng JNKDN | 0.13 |
| uPA-MP + MEKK + 40 ng JNKDN | 0.02 |
| uPA-MP + MEKK + 400 ng JNKDN | 0.01 |
| uPA-MP + MEK1 | 1 |
| uPA-MP + MEK1 + 50 ng JNKDN | 0.71 |
| uPA-MP + MEK1 + 100 ng JNKDN | 1.12 |
Constructs . | Fold decrease . |
|---|---|
| uPA-MP + MEKK | 1 |
| uPA-MP + MEKK + 4 ng JNKDN | 0.13 |
| uPA-MP + MEKK + 40 ng JNKDN | 0.02 |
| uPA-MP + MEKK + 400 ng JNKDN | 0.01 |
| uPA-MP + MEK1 | 1 |
| uPA-MP + MEK1 + 50 ng JNKDN | 0.71 |
| uPA-MP + MEK1 + 100 ng JNKDN | 1.12 |