Aggregation responses to submaximal stimulation in FVB and C57 strain
Assay . | FVB . | C57 . | P . |
|---|---|---|---|
| Soluble collagen, 34 μg/mL, n = 5 | |||
| Maximum aggregation, % | 14.6 ± 26.4 | 64.2 ± 26.3 | < .02 |
| Lag time, min | 8.16 ± 1.8 | 3.98 ± 1.12 | .002 |
| Fibrillar collagen, 1 μg/mL | |||
| Maximum aggregation, % | 21.1 ± 20.6 | 65.2 ± 14.9 | .0003 |
| Lag time, min | 4.36 ± 2.1 | 2.19 ± 0.99 | .02 |
| CRP, 0.5 μg/mL, n = 6 | |||
| Maximum aggregation, % | 74 ± 12.7 | 74.2 ± 11.5 | NS |
| Lag time, min | 0.51 ± 0.07 | 0.5 ± 0.1 | NS |
| Rhodocytin, 20 nM, n = 3 | |||
| Maximum aggregation, % | 73.7 ± 11.6 | 76 ± 9.5 | NS |
| Lag time, min | 1.38 ± 0.22 | 0.97 ± 0.06 | < .04 |
Assay . | FVB . | C57 . | P . |
|---|---|---|---|
| Soluble collagen, 34 μg/mL, n = 5 | |||
| Maximum aggregation, % | 14.6 ± 26.4 | 64.2 ± 26.3 | < .02 |
| Lag time, min | 8.16 ± 1.8 | 3.98 ± 1.12 | .002 |
| Fibrillar collagen, 1 μg/mL | |||
| Maximum aggregation, % | 21.1 ± 20.6 | 65.2 ± 14.9 | .0003 |
| Lag time, min | 4.36 ± 2.1 | 2.19 ± 0.99 | .02 |
| CRP, 0.5 μg/mL, n = 6 | |||
| Maximum aggregation, % | 74 ± 12.7 | 74.2 ± 11.5 | NS |
| Lag time, min | 0.51 ± 0.07 | 0.5 ± 0.1 | NS |
| Rhodocytin, 20 nM, n = 3 | |||
| Maximum aggregation, % | 73.7 ± 11.6 | 76 ± 9.5 | NS |
| Lag time, min | 1.38 ± 0.22 | 0.97 ± 0.06 | < .04 |
All data are expressed as means ± SD.
NS indicates not significant.