Platelet function testing
Agonist . | Patient . | Controls . |
|---|---|---|
| ADP, 8 μM | 40 | 75 ± 16 |
| TRAP, 50 μM | 20 | 77 ± 10 |
| Epinephrine, 2 μM | 0 | 41 ± 18 |
| Arachidonic acid, 0.5 mg/mL | 40 | 74 ± 12 |
| Collagen, 2 μg/mL | 0 | 40 ± 27 |
| Collagen, 20 μg/mL | 10 | 76 ± 11 |
| Ristocetin, 1.5 mg/mL | 60 | 79 ± 16 |
Agonist . | Patient . | Controls . |
|---|---|---|
| ADP, 8 μM | 40 | 75 ± 16 |
| TRAP, 50 μM | 20 | 77 ± 10 |
| Epinephrine, 2 μM | 0 | 41 ± 18 |
| Arachidonic acid, 0.5 mg/mL | 40 | 74 ± 12 |
| Collagen, 2 μg/mL | 0 | 40 ± 27 |
| Collagen, 20 μg/mL | 10 | 76 ± 11 |
| Ristocetin, 1.5 mg/mL | 60 | 79 ± 16 |
Platelet aggregation was studied using citrated PRP. Results are expressed as maximum light transmission changes. The platelet count for both the patient and controls (n = 6; ± SD) was 60 000/μL. The results for the patient are typical of those obtained on 4 different occasions. Collagen was from Sigma.