Table 1.

Age-dependent increase of inflammatory lesions in tc-ptp−/−mice



No. of mice with mononuclear infiltrate
Age and organ
No infiltrate
Mild to severe infiltrate
Days 6-7   
Salivary gland   ⅓   ⅔  
Stomach   ½   ½  
Days 13-14   
Salivary gland   ⅓   ⅔  
Stomach   ½   ½  
Heart   0/2   2/2  
Days 20-21   
Salivary gland   0/3   3/3  
Stomach   0/3   3/3  
Liver   ⅔   ⅓  
Heart   0/3   3/3  
Kidney   ⅓   ⅔  
Skin
 

 

 


No. of mice with mononuclear infiltrate
Age and organ
No infiltrate
Mild to severe infiltrate
Days 6-7   
Salivary gland   ⅓   ⅔  
Stomach   ½   ½  
Days 13-14   
Salivary gland   ⅓   ⅔  
Stomach   ½   ½  
Heart   0/2   2/2  
Days 20-21   
Salivary gland   0/3   3/3  
Stomach   0/3   3/3  
Liver   ⅔   ⅓  
Heart   0/3   3/3  
Kidney   ⅓   ⅔  
Skin
 

 

 

Summary of pathology results in tc-ptp−/− mice at 1, 2, and 3 weeks after birth. The tc-ptp+/+ and tc-ptp+/− littermate controls showed no infiltrate.

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