Age-dependent increase of inflammatory lesions in tc-ptp−/−mice
. | No. of mice with mononuclear infiltrate . | . | |
---|---|---|---|
Age and organ . | No infiltrate . | Mild to severe infiltrate . | |
Days 6-7 | |||
Salivary gland | ⅓ | ⅔ | |
Stomach | ½ | ½ | |
Days 13-14 | |||
Salivary gland | ⅓ | ⅔ | |
Stomach | ½ | ½ | |
Heart | 0/2 | 2/2 | |
Days 20-21 | |||
Salivary gland | 0/3 | 3/3 | |
Stomach | 0/3 | 3/3 | |
Liver | ⅔ | ⅓ | |
Heart | 0/3 | 3/3 | |
Kidney | ⅓ | ⅔ | |
Skin | ⅔ | ⅓ |
. | No. of mice with mononuclear infiltrate . | . | |
---|---|---|---|
Age and organ . | No infiltrate . | Mild to severe infiltrate . | |
Days 6-7 | |||
Salivary gland | ⅓ | ⅔ | |
Stomach | ½ | ½ | |
Days 13-14 | |||
Salivary gland | ⅓ | ⅔ | |
Stomach | ½ | ½ | |
Heart | 0/2 | 2/2 | |
Days 20-21 | |||
Salivary gland | 0/3 | 3/3 | |
Stomach | 0/3 | 3/3 | |
Liver | ⅔ | ⅓ | |
Heart | 0/3 | 3/3 | |
Kidney | ⅓ | ⅔ | |
Skin | ⅔ | ⅓ |
Summary of pathology results in tc-ptp−/− mice at 1, 2, and 3 weeks after birth. The tc-ptp+/+ and tc-ptp+/− littermate controls showed no infiltrate.