Characteristics of 134 patients with high-risk MDS or AML in the elderly by treatment
. | FLAG . | ARA-C + G-CSF . |
|---|---|---|
| Total no. patients (%) | 65 (100) | 69 (100) |
| Sex, n (%) | ||
| Male | 46 (71) | 41 (59) |
| Female | 19 (29) | 28 (41) |
| Age, y, median (range) | 66 (48-75) | 65 (24-75) |
| Age group, n (%) | ||
| 60 y or younger | 8 (12) | 8 (12) |
| Older than 60 y | 57 (88) | 61 (88) |
| WHO performance status, n (%) | ||
| 0 | 39 (60) | 42 (61) |
| 1 | 25 (38) | 23 (33) |
| 2 | 1 (2) | 4 (6) |
| FAB classification, n (%) | ||
| MDS | 43 (66) | 48 (70) |
| RA | 3 (5) | 1 (1) |
| RARS | 1 (2) | 0 |
| RAEB | 15 (23) | 15 (22) |
| RAEB-t | 14 (22) | 22 (32) |
| CMML | 10 (15) | 10 (14) |
| AML | 22 (34) | 21 (30) |
| IPSS for MDS, n (%) | ||
| Low | 3 (7) | 1 (2) |
| Intermediate-1 | 9 (21) | 11 (23) |
| Intermediate-2 | 19 (44) | 15 (31) |
| High | 10 (23) | 15 (31) |
| Not assessed | 2 (5) | 6 (13) |
| Cytogenetic risk category, n (%) | ||
| Favorable risk | 0 | 1 (1) |
| Standard risk | 40 (70) | 44 (77) |
| Poor risk | 17 (30) | 13 (22) |
| WBC count, × 109/L, median (range) | 3.0 (0.4-109) | 4.4 (0.5-215) |
| Platelet count, n (%) | ||
| Below 100 × 109/L | 50 (77) | 53 (78) |
| More than 100 × 109/L | 15 (23) | 15 (22) |
. | FLAG . | ARA-C + G-CSF . |
|---|---|---|
| Total no. patients (%) | 65 (100) | 69 (100) |
| Sex, n (%) | ||
| Male | 46 (71) | 41 (59) |
| Female | 19 (29) | 28 (41) |
| Age, y, median (range) | 66 (48-75) | 65 (24-75) |
| Age group, n (%) | ||
| 60 y or younger | 8 (12) | 8 (12) |
| Older than 60 y | 57 (88) | 61 (88) |
| WHO performance status, n (%) | ||
| 0 | 39 (60) | 42 (61) |
| 1 | 25 (38) | 23 (33) |
| 2 | 1 (2) | 4 (6) |
| FAB classification, n (%) | ||
| MDS | 43 (66) | 48 (70) |
| RA | 3 (5) | 1 (1) |
| RARS | 1 (2) | 0 |
| RAEB | 15 (23) | 15 (22) |
| RAEB-t | 14 (22) | 22 (32) |
| CMML | 10 (15) | 10 (14) |
| AML | 22 (34) | 21 (30) |
| IPSS for MDS, n (%) | ||
| Low | 3 (7) | 1 (2) |
| Intermediate-1 | 9 (21) | 11 (23) |
| Intermediate-2 | 19 (44) | 15 (31) |
| High | 10 (23) | 15 (31) |
| Not assessed | 2 (5) | 6 (13) |
| Cytogenetic risk category, n (%) | ||
| Favorable risk | 0 | 1 (1) |
| Standard risk | 40 (70) | 44 (77) |
| Poor risk | 17 (30) | 13 (22) |
| WBC count, × 109/L, median (range) | 3.0 (0.4-109) | 4.4 (0.5-215) |
| Platelet count, n (%) | ||
| Below 100 × 109/L | 50 (77) | 53 (78) |
| More than 100 × 109/L | 15 (23) | 15 (22) |
RARS indicates refractory anemia with ringed sideroblasts.