Table 4.

Yields of TNCs, CD34+ cells, CFCs, and LTC-ICs per leukapheresis following chemotherapy plus either rhG-CSF (first cycle) or rhGH/rhG-CSF (second cycle)



TNCs, × 108/kg

CD34+ cells, × 106/kg

CFCs, × 105/kg

LTC-Ics, × 104/kg
Case
First cycle
Second cycle
First cycle
Second cycle
First cycle
Second cycle
First cycle
Second cycle
1   2.7   5.7   1.1   5.0   3.6   10   0.5   1.7  
2   —   3.5   —   1.7   —   4.3   —   0.8  
3   3.3   4.5   0.8   2.3   3.2   12   0.1   0.8  
4   2.0   1.8   1.1   1.5   3.0   5.0   1.6   1.2  
5   2.7   2.7   1.1   2.3   6.5   6.3   0.7   3.2  
6   3.8   4.5   0.6   0.8   3.4   5.9   0.2   2.5  
7   2.9   12   1.5   1.7   6.3   7.2   0.5   2.3  
8   —   7.0   —   2.5   —   6.2   —   1.8  
9   —   3.7   —   2.5   —   3.7   —   2.0  
10   —   6.9   —   2.2   —   7.5   —   0.8  
11   —   4.2   —   3.8   —   28   —   7.9  
12   4.0   5.5   0.9   1.2   1.3   3.1   0.2   1.0  
13   3.5   3.4   2.0   3.7   2.7   8.2   0.5   1.6  
14   —   4.8   —   1.9   —   5.4   —   0.5  
15   —   3.8   —   2.6   —   9.8   —   1.5  
16   —   —   —   —   —   —   —   —  
Median(range)
 
3.1 (2-4)
 
4.5* (1.8-12)
 
1.1 (0.6-2)
 
2.3 (0.8-5)
 
3.3 (1.3-6.5)
 
6.3 (3.1-28)
 
0.5 (0.1-1.6)
 
1.6 (0.5-7.9)
 


TNCs, × 108/kg

CD34+ cells, × 106/kg

CFCs, × 105/kg

LTC-Ics, × 104/kg
Case
First cycle
Second cycle
First cycle
Second cycle
First cycle
Second cycle
First cycle
Second cycle
1   2.7   5.7   1.1   5.0   3.6   10   0.5   1.7  
2   —   3.5   —   1.7   —   4.3   —   0.8  
3   3.3   4.5   0.8   2.3   3.2   12   0.1   0.8  
4   2.0   1.8   1.1   1.5   3.0   5.0   1.6   1.2  
5   2.7   2.7   1.1   2.3   6.5   6.3   0.7   3.2  
6   3.8   4.5   0.6   0.8   3.4   5.9   0.2   2.5  
7   2.9   12   1.5   1.7   6.3   7.2   0.5   2.3  
8   —   7.0   —   2.5   —   6.2   —   1.8  
9   —   3.7   —   2.5   —   3.7   —   2.0  
10   —   6.9   —   2.2   —   7.5   —   0.8  
11   —   4.2   —   3.8   —   28   —   7.9  
12   4.0   5.5   0.9   1.2   1.3   3.1   0.2   1.0  
13   3.5   3.4   2.0   3.7   2.7   8.2   0.5   1.6  
14   —   4.8   —   1.9   —   5.4   —   0.5  
15   —   3.8   —   2.6   —   9.8   —   1.5  
16   —   —   —   —   —   —   —   —  
Median(range)
 
3.1 (2-4)
 
4.5* (1.8-12)
 
1.1 (0.6-2)
 
2.3 (0.8-5)
 
3.3 (1.3-6.5)
 
6.3 (3.1-28)
 
0.5 (0.1-1.6)
 
1.6 (0.5-7.9)
 

P values derived as compared with the first cycle by Wilcoxon matched pairs test (2-tail):

*

P ≤ 08.

P ≤ 008.

P ≤ 01.

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