Table 6. CD34 cell mobilization and... | American Society of Hematology

Table 6.

CD34⁺ cell mobilization and collection in hard-to-mobilize historical controls receiving 2 consecutive cycles of the same chemotherapy regimen plus rhG-CSF at either 5 μg/kg/d (first cycle) or 15 μg/kg/d (second cycle)

			WBCs × 10⁹/L, peak value			CD34⁺ cells/μL, peak value			Leukapheresis, no.			CD34⁺ cells/leukapheresis, 10⁶/kg
Case	Diagnosis	Chemotherapy	First cycle	Second cycle	First cycle	Second cycle	First cycle	Second cycle	First cycle	Second cycle	First cycle	Second cycle
1	HL	IFO-VNB	18	23	2	17	—	2	—	2.15	—	4.3
2	HL	IFO-VNB	19	17	10	6	1	—	1.5	—	1.5	—
3	FL	DHAP	34	47	4	5	—	—	—	—	—	—
4	MM	D-PACE	25	45	5	10	—	1	—	0.5	—	0.5
5	HL	IFO-VNB	17	21	5	30	—	4	—	3	—	12
6	MCL	DHAP	50	52	5	4	—	—	—	—	—	—
7	FL	DHAP	32	65	17	10	1	1	1.2	2.2	1.2	2.2
8	DLBCL	DHAP	14	36	10	33	1	3	1.5	1.6	1.5	4.7
9	HL	IFO-VNB	39	65	10	28	1	4	0.3	1.5	0.3	6
10	DLBCL	DHAP	20	29	2	2	—	—	—	—	—	—
11	FL	DHAP	12	43	25	11	1	1	1.9	1	1.9	1
12	MM	D-PACE	27	35	2	5	—	—	—	—	—	—
13	MM	D-PACE	28	23	9	11	—	1	—	0.6	—	0.6
14	FL	DHAP	29	34	17	12	1	1	1.4	0.7	1.4	0.7

			WBCs × 10⁹/L, peak value			CD34⁺ cells/μL, peak value			Leukapheresis, no.			CD34⁺ cells/leukapheresis, 10⁶/kg
Case	Diagnosis	Chemotherapy	First cycle	Second cycle	First cycle	Second cycle	First cycle	Second cycle	First cycle	Second cycle	First cycle	Second cycle
1	HL	IFO-VNB	18	23	2	17	—	2	—	2.15	—	4.3
2	HL	IFO-VNB	19	17	10	6	1	—	1.5	—	1.5	—
3	FL	DHAP	34	47	4	5	—	—	—	—	—	—
4	MM	D-PACE	25	45	5	10	—	1	—	0.5	—	0.5
5	HL	IFO-VNB	17	21	5	30	—	4	—	3	—	12
6	MCL	DHAP	50	52	5	4	—	—	—	—	—	—
7	FL	DHAP	32	65	17	10	1	1	1.2	2.2	1.2	2.2
8	DLBCL	DHAP	14	36	10	33	1	3	1.5	1.6	1.5	4.7
9	HL	IFO-VNB	39	65	10	28	1	4	0.3	1.5	0.3	6
10	DLBCL	DHAP	20	29	2	2	—	—	—	—	—	—
11	FL	DHAP	12	43	25	11	1	1	1.9	1	1.9	1
12	MM	D-PACE	27	35	2	5	—	—	—	—	—	—
13	MM	D-PACE	28	23	9	11	—	1	—	0.6	—	0.6
14	FL	DHAP	29	34	17	12	1	1	1.4	0.7	1.4	0.7

IFO-VNB indicates ifosfamide, vinorelbine; MCL, mantle cell lymphoma. Other abbreviations are explained in Tables 1 and 2.

View Large

This Feature Is Available To Subscribers Only