The effect of rapamycin and dexamethasone on distribution of cell cycle phases in 2 MM cell lines
Cell line and treatment . | G0/G1 . | S . | G2/M . |
|---|---|---|---|
| Karpas 707 | |||
| Control | 52 ± 4 | 36 ± 2 | 12 ± 3 |
| Rap | 78 ± 4 | 14 ± 1 | 8 ± 4 |
| Dex | 54 ± 2 | 34 ± 5 | 12 ± 3 |
| Rap + Dex | 75 ± 1 | 16 ± 3 | 9 ± 4 |
| U-1958 | |||
| Control | 52 ± 4 | 32 ± 1 | 15 ± 2 |
| Rap | 69 ± 3 | 22 ± 4 | 9 ± 0 |
| Dex | 52 ± 3 | 33 ± 2 | 15 ± 0 |
| Rap + Dex | 66 ± 5 | 27 ± 5 | 7 ± 1 |
Cell line and treatment . | G0/G1 . | S . | G2/M . |
|---|---|---|---|
| Karpas 707 | |||
| Control | 52 ± 4 | 36 ± 2 | 12 ± 3 |
| Rap | 78 ± 4 | 14 ± 1 | 8 ± 4 |
| Dex | 54 ± 2 | 34 ± 5 | 12 ± 3 |
| Rap + Dex | 75 ± 1 | 16 ± 3 | 9 ± 4 |
| U-1958 | |||
| Control | 52 ± 4 | 32 ± 1 | 15 ± 2 |
| Rap | 69 ± 3 | 22 ± 4 | 9 ± 0 |
| Dex | 52 ± 3 | 33 ± 2 | 15 ± 0 |
| Rap + Dex | 66 ± 5 | 27 ± 5 | 7 ± 1 |
Karpas 707 and U-1958 cells were treated with rapamycin (Rap) and/or dexamethasone (Dex) for 48 hours followed by analysis using the Vindelöv method.38 Three independent experiments per cell line were performed, and results are presented as mean percentage ± SD where n = 3.