Outcome with conventional chemotherapy for adults with Ph-positive ALL
First author/reference no. . | Year . | No. . | % CR . | Median CRD, mo . | Median survival, mo . | % DFS (y) . | % OS (y) . |
|---|---|---|---|---|---|---|---|
| Bloomfield54 | 1989 | 29 | 46 | 7 | 11 | — | — |
| Secker-Walker23 | 1991 | 23 | 64 | — | 8 | — | — |
| Gotz55 | 1992 | 25 | 76 | 9 | 13 | — | 6 (3) |
| Westbrook56 | 1992 | 12 | 71 | 10 | 11 | — | — |
| Larson57 | 1995 | 25 | 70 | 7 | — | 11 (3) | 16 (3) |
| GFCH58 | 1996 | 127 | 59 | — | 5 | — | 5 (3) |
| Chim59 | 1997 | 6 | 83 | — | — | — | — |
| Secker-Walker60 | 1997 | 40 | 83 | 11 | — | 13 (3) | — |
| Thomas61 | 1998 | 43 | 64 | 6 | 9 | — | — |
| Wetzler62 | 1999 | 67 | 82 | 11 | 16 | 8 (5) | 11 (5) |
| Faderl7 | 2000 | 67 | 90 | 10 | 16 | — | — |
| Ko63 | 2001 | 26 | 64 | — | — | 0 (5) | 7 (5) |
| Thomas64 | 2001 | 51 | — | — | — | 13 (5) | 10 (5) |
| Annino65 | 2002 | 47 | 83 | 9 | — | — | — |
| Dombret66 | 2002 | 154 | 67 | — | — | — | 19 (3) |
| Thomas (current study) | 2003 | 20 | 100 | 15+ | 18+ | 84 (2) | 64 (2) |
First author/reference no. . | Year . | No. . | % CR . | Median CRD, mo . | Median survival, mo . | % DFS (y) . | % OS (y) . |
|---|---|---|---|---|---|---|---|
| Bloomfield54 | 1989 | 29 | 46 | 7 | 11 | — | — |
| Secker-Walker23 | 1991 | 23 | 64 | — | 8 | — | — |
| Gotz55 | 1992 | 25 | 76 | 9 | 13 | — | 6 (3) |
| Westbrook56 | 1992 | 12 | 71 | 10 | 11 | — | — |
| Larson57 | 1995 | 25 | 70 | 7 | — | 11 (3) | 16 (3) |
| GFCH58 | 1996 | 127 | 59 | — | 5 | — | 5 (3) |
| Chim59 | 1997 | 6 | 83 | — | — | — | — |
| Secker-Walker60 | 1997 | 40 | 83 | 11 | — | 13 (3) | — |
| Thomas61 | 1998 | 43 | 64 | 6 | 9 | — | — |
| Wetzler62 | 1999 | 67 | 82 | 11 | 16 | 8 (5) | 11 (5) |
| Faderl7 | 2000 | 67 | 90 | 10 | 16 | — | — |
| Ko63 | 2001 | 26 | 64 | — | — | 0 (5) | 7 (5) |
| Thomas64 | 2001 | 51 | — | — | — | 13 (5) | 10 (5) |
| Annino65 | 2002 | 47 | 83 | 9 | — | — | — |
| Dombret66 | 2002 | 154 | 67 | — | — | — | 19 (3) |
| Thomas (current study) | 2003 | 20 | 100 | 15+ | 18+ | 84 (2) | 64 (2) |
CR indicates complete remission; CRD, CR duration; DFS, disease-free survival; OS, overall survival; —, not reported; and GFCH, Group Francais de Cytogenetique Hematologique.