Correlation of CDR3 length and VHDHJH utilization in childhood B-lineage ALL
Gene family . | . | . | . | CDR3 length, bp . | P . |
|---|---|---|---|---|---|
| No. | Mean | SD | Median | ||
| VH | .006 | ||||
| VH1 | 62 | 29.7 | 15.9 | 26.5 | |
| VH2 | 22 | 31.9 | 12.0 | 31.5 | |
| VH3 | 192 | 36.8 | 37.7 | 30.0 | |
| VH4 | 60 | 32.1 | 16.3 | 31.5 | |
| VH5 | 10 | 33.4 | 15.2 | 33.5 | |
| VH6 | 35 | 22.3 | 11.9 | 21.0 | |
| DH | < .0001 | ||||
| DH1 | 23 | 25.3 | 10.1 | 24.0 | |
| DH2 | 108 | 41.4 | 29.4 | 36.5 | |
| DH3 | 97 | 37.1 | 24.5 | 34.0 | |
| DH4 | 12 | 31.3 | 12.8 | 28.5 | |
| DH5 | 15 | 27.9 | 9.8 | 27.0 | |
| DH6 | 37 | 35.0 | 36.8 | 26.0 | |
| DH7 | 12 | 20.9 | 8.7 | 20.5 | |
| JH | .16 | ||||
| JH1 | 6 | 48.0 | 21.4 | 44.0 | |
| JH2 | 11 | 33.5 | 19.4 | 34.0 | |
| JH3 | 7 | 31.1 | 16.6 | 33.0 | |
| JH4 | 148 | 29.9 | 15.3 | 27.0 | |
| JH5 | 78 | 32.0 | 28.4 | 30.0 | |
| JH6 | 131 | 37.1 | 40.3 | 31.0 |
Gene family . | . | . | . | CDR3 length, bp . | P . |
|---|---|---|---|---|---|
| No. | Mean | SD | Median | ||
| VH | .006 | ||||
| VH1 | 62 | 29.7 | 15.9 | 26.5 | |
| VH2 | 22 | 31.9 | 12.0 | 31.5 | |
| VH3 | 192 | 36.8 | 37.7 | 30.0 | |
| VH4 | 60 | 32.1 | 16.3 | 31.5 | |
| VH5 | 10 | 33.4 | 15.2 | 33.5 | |
| VH6 | 35 | 22.3 | 11.9 | 21.0 | |
| DH | < .0001 | ||||
| DH1 | 23 | 25.3 | 10.1 | 24.0 | |
| DH2 | 108 | 41.4 | 29.4 | 36.5 | |
| DH3 | 97 | 37.1 | 24.5 | 34.0 | |
| DH4 | 12 | 31.3 | 12.8 | 28.5 | |
| DH5 | 15 | 27.9 | 9.8 | 27.0 | |
| DH6 | 37 | 35.0 | 36.8 | 26.0 | |
| DH7 | 12 | 20.9 | 8.7 | 20.5 | |
| JH | .16 | ||||
| JH1 | 6 | 48.0 | 21.4 | 44.0 | |
| JH2 | 11 | 33.5 | 19.4 | 34.0 | |
| JH3 | 7 | 31.1 | 16.6 | 33.0 | |
| JH4 | 148 | 29.9 | 15.3 | 27.0 | |
| JH5 | 78 | 32.0 | 28.4 | 30.0 | |
| JH6 | 131 | 37.1 | 40.3 | 31.0 |
P values were obtained using the Kruskal-Wallis test, 2-sided.
CDR indicates complementarity-determining region; and bp, base pairs.