Association between etiology of TTP and ADAMTS13 activity
Etiology . | ADAMTS13 activity lower than 5% . | ADAMTS13 activity from 5%-50% . | ADAMTS13 activity higher than 50% . | +ADAMTS13 inhibitor . | Total . |
|---|---|---|---|---|---|
| Idiopathic | 16 | 4 | 0 | 7 | 20 |
| HSCT and cyclosporine | 0 | 4 | 4 | 0 | 8 |
| Cancer and chemotherapy | 0 | 2 | 1 | 0 | 3 |
| Clopidogrel | 0 | 0 | 1 | 0 | 1 |
| Pregnancy | 0 | 1 | 1 | 0 | 2 |
| Other | 0 | 1 | 2 | 0 | 3 |
| Total | 16 | 12 | 9 | 7 | 37 |
Etiology . | ADAMTS13 activity lower than 5% . | ADAMTS13 activity from 5%-50% . | ADAMTS13 activity higher than 50% . | +ADAMTS13 inhibitor . | Total . |
|---|---|---|---|---|---|
| Idiopathic | 16 | 4 | 0 | 7 | 20 |
| HSCT and cyclosporine | 0 | 4 | 4 | 0 | 8 |
| Cancer and chemotherapy | 0 | 2 | 1 | 0 | 3 |
| Clopidogrel | 0 | 0 | 1 | 0 | 1 |
| Pregnancy | 0 | 1 | 1 | 0 | 2 |
| Other | 0 | 1 | 2 | 0 | 3 |
| Total | 16 | 12 | 9 | 7 | 37 |
Values in the table indicate the number of patients in each category. ADAMTS13 activity and inhibitors were measured on plasma collected immediately before the first plasma exchange treatment as described in “Patients, materials, and methods.” HSCT indicates hematopoietic stem cell transplantation.