Clinical and laboratory characteristics of patients
Characteristic . | . |
|---|---|
| Sex, F/M | 4/1 |
| Race, no. of AA/W/other | 16/20/1 |
| Median age, y (range) | 47 (16-79) |
| Mean lactate dehydrogenase level, IU/dL (range) | 939 (328-28000) |
| Median hematocrit (range) | 0.28 (0.129-0.37) |
| Median platelet count, × 109/L (range) | 18 (2-147) |
| No. of patients with renal dysfunction, creatinine level more than 132.6 μM | 17 |
| Median creatinine level, μM (range) | 176.8 (44.2-302.56) |
| No. of patients with initial acute event | 26 |
| No. of patients with multiple acute events | 11 |
| No. of patients with fever | 13 |
| No. of patients with neurologic symptoms | 21 |
| No. of patients who required dialysis during the hospitalization | 7 |
| No. of patients who received corticosteroid treatment | 23 |
| No. of patients who received vincristine treatment | 10 |
| No. of patients who received cyclosporine treatment | 1 |
| No. of patients who received cyclophosphamide treatment | 4 |
| No. of patients who received rituximab treatment | 1 |
| No. of patients who had splenectomy | 8 |
Characteristic . | . |
|---|---|
| Sex, F/M | 4/1 |
| Race, no. of AA/W/other | 16/20/1 |
| Median age, y (range) | 47 (16-79) |
| Mean lactate dehydrogenase level, IU/dL (range) | 939 (328-28000) |
| Median hematocrit (range) | 0.28 (0.129-0.37) |
| Median platelet count, × 109/L (range) | 18 (2-147) |
| No. of patients with renal dysfunction, creatinine level more than 132.6 μM | 17 |
| Median creatinine level, μM (range) | 176.8 (44.2-302.56) |
| No. of patients with initial acute event | 26 |
| No. of patients with multiple acute events | 11 |
| No. of patients with fever | 13 |
| No. of patients with neurologic symptoms | 21 |
| No. of patients who required dialysis during the hospitalization | 7 |
| No. of patients who received corticosteroid treatment | 23 |
| No. of patients who received vincristine treatment | 10 |
| No. of patients who received cyclosporine treatment | 1 |
| No. of patients who received cyclophosphamide treatment | 4 |
| No. of patients who received rituximab treatment | 1 |
| No. of patients who had splenectomy | 8 |
Race is indicated as African American (AA), white (W), or other. Signs and symptoms were recorded on the date of admission. Fever was defined as temperature of at least 37.5°C.