Table 2.

Cellularity in hematopoietic organs of WT and Hoxb4-deficient mice


Hematopoietic parameter

Hoxb4+/+

Hoxb4-/-

P
Spleen weight, mg   105 ± 13   89 ± 9   .05  
Spleen cellularity, × 106  154 ± 20   128 ± 25   .03  
Red blood cell count, × 1012/L   8 ± 0.5   7.6 ± 0.4   .04  
Hemoglobin, g/L   142 ± 6   136 ± 5   .04  
White blood cell count, × 109/L   4.3 ± 0.6   4.0 ± 0.6   .5  
Bone marrow cellularity, × 106/2 femurs
 
56 ± 8
 
46 ± 6
 
.04
 

Hematopoietic parameter

Hoxb4+/+

Hoxb4-/-

P
Spleen weight, mg   105 ± 13   89 ± 9   .05  
Spleen cellularity, × 106  154 ± 20   128 ± 25   .03  
Red blood cell count, × 1012/L   8 ± 0.5   7.6 ± 0.4   .04  
Hemoglobin, g/L   142 ± 6   136 ± 5   .04  
White blood cell count, × 109/L   4.3 ± 0.6   4.0 ± 0.6   .5  
Bone marrow cellularity, × 106/2 femurs
 
56 ± 8
 
46 ± 6
 
.04
 

n = 10 mice/genotype, 12 to 16 weeks of age. Values are mean ± SD.