Percentage of whites and African Americans with each cytogenetic abnormality
Risk group . | Whites, n (%) . | African Americans, n (%) . | Total, n (%) . | P . |
|---|---|---|---|---|
| Favorable | ||||
| t(8;21) | 72 (5.8) | 24 (17.0) | 96 (7.0) | < .0001 |
| inv(16) or t(16;16) | 101 (8.1) | 8 (5.7) | 109 (7.9) | .40 |
| Intermediate | ||||
| Normal | 644 (51.9) | 53 (37.5) | 697 (50.6) | .0014 |
| del(9q) | 34 (2.7) | 5 (3.5) | 39 (2.8) | .59 |
| t(9;11) | 31 (2.5) | 3 (2.1) | 34 (2.5) | 1.0 |
| del(5q) | 51 (4.1) | 8 (5.7) | 59 (4.3) | .38 |
| loss of 7q | 23 (1.9) | 5 (3.5) | 28 (2.0) | .20 |
| +11 | 25 (2.0) | 3 (2.1) | 28 (2.0) | .76 |
| del(11q) | 9 (0.7) | 1 (0.7) | 10 (0.7) | 1.0 |
| abn(12p) | 38 (3.1) | 6 (4.3) | 44 (3.2) | .44 |
| +13 | 32 (2.6) | 5 (3.5) | 37 (2.7) | .42 |
| del(20q) | 14 (1.1) | 2 (1.4) | 16 (1.2) | .67 |
| +21 | 36 (2.9) | 1 (0.7) | 37 (2.7) | .17 |
| -Y | 44 (3.5) | 7 (5.0) | 51 (3.7) | .35 |
| Unfavorable | ||||
| Complex, 3 or more abn | 131 (10.5) | 18 (12.8) | 149 (10.8) | .30 |
| inv(3) or t(3;3) | 18 (1.5) | 1 (0.7) | 19 (1.4) | .71 |
| t(6;9) | 7 (0.6) | 3 (2.1) | 10 (0.7) | .07 |
| t(6;11) | 7 (0.6) | 4 (2.8) | 11 (0.8) | .02 |
| -7 | 37 (3.0) | 5 (3.6) | 42 (3.0) | .61 |
| +8 | 139 (11.2) | 22 (15.6) | 161 (11.7) | .13 |
| t(11;19) (q23;p13.1) | 9 (0.7) | 0 (0) | 9 (0.7) | .61 |
Risk group . | Whites, n (%) . | African Americans, n (%) . | Total, n (%) . | P . |
|---|---|---|---|---|
| Favorable | ||||
| t(8;21) | 72 (5.8) | 24 (17.0) | 96 (7.0) | < .0001 |
| inv(16) or t(16;16) | 101 (8.1) | 8 (5.7) | 109 (7.9) | .40 |
| Intermediate | ||||
| Normal | 644 (51.9) | 53 (37.5) | 697 (50.6) | .0014 |
| del(9q) | 34 (2.7) | 5 (3.5) | 39 (2.8) | .59 |
| t(9;11) | 31 (2.5) | 3 (2.1) | 34 (2.5) | 1.0 |
| del(5q) | 51 (4.1) | 8 (5.7) | 59 (4.3) | .38 |
| loss of 7q | 23 (1.9) | 5 (3.5) | 28 (2.0) | .20 |
| +11 | 25 (2.0) | 3 (2.1) | 28 (2.0) | .76 |
| del(11q) | 9 (0.7) | 1 (0.7) | 10 (0.7) | 1.0 |
| abn(12p) | 38 (3.1) | 6 (4.3) | 44 (3.2) | .44 |
| +13 | 32 (2.6) | 5 (3.5) | 37 (2.7) | .42 |
| del(20q) | 14 (1.1) | 2 (1.4) | 16 (1.2) | .67 |
| +21 | 36 (2.9) | 1 (0.7) | 37 (2.7) | .17 |
| -Y | 44 (3.5) | 7 (5.0) | 51 (3.7) | .35 |
| Unfavorable | ||||
| Complex, 3 or more abn | 131 (10.5) | 18 (12.8) | 149 (10.8) | .30 |
| inv(3) or t(3;3) | 18 (1.5) | 1 (0.7) | 19 (1.4) | .71 |
| t(6;9) | 7 (0.6) | 3 (2.1) | 10 (0.7) | .07 |
| t(6;11) | 7 (0.6) | 4 (2.8) | 11 (0.8) | .02 |
| -7 | 37 (3.0) | 5 (3.6) | 42 (3.0) | .61 |
| +8 | 139 (11.2) | 22 (15.6) | 161 (11.7) | .13 |
| t(11;19) (q23;p13.1) | 9 (0.7) | 0 (0) | 9 (0.7) | .61 |
Number of patients tested were as follows: whites, n = 1242; African Americans, n = 141; total, n = 1383. Abnormalities are ordered in this table according to the way in which they were used to form cytogenetic risk groups. Percentages do not sum up to 100% because patients could have more than one abnormality.