Deaths in the cohort
Cause of death . | No. . | Genotype . | Age at death, y . |
|---|---|---|---|
| Probably related to SCD | |||
| Pneumococcal sepsis | 4 | SS | 2.5, 3.1, 5.4, 6.0 |
| Acute chest syndrome | 3 | SS | 4.8, 5.5, 5.8 |
| Multiorgan failure syndrome | 2 | SS | 4.8, 14.8 |
| H influenzae type b sepsis | 1 | SS | 1.9 |
| Myocardial infarction | 1 | SS | 13.7 |
| Complications of recurrent strokes | 1 | SS | 7.8 |
| Ceftriaxone-induced hemolysis | 1 | SS | 2.0 |
| Multifactorial | 2 | SS | 0.9, 4.0 |
| Total | 15 | 4.8* | |
| Probably unrelated to SCD | |||
| Motor vehicle collision | 2 | SS, SC | 1.8, 1.9 |
| Drowning | 1 | SS | 1.2 |
| Complex congenital heart disease (CHD) | 1 | SS | 1.0 |
| Acute viral myocarditis | 1 | SS | 1.1 |
| Down syndrome, Hirschsprung disease, complex CHD | 1 | SS | 5.2 |
| Glutaric acidemia type 2 | 1 | SS | 12.1 |
| Closed head injury | 1 | SS | 17.1 |
| γδ-T-cell lymphoma | 1 | SC | 12.1 |
| Metabolic disorder | 1 | Sβ+ | 1.7 |
| Total | 10 | 1.9* |
Cause of death . | No. . | Genotype . | Age at death, y . |
|---|---|---|---|
| Probably related to SCD | |||
| Pneumococcal sepsis | 4 | SS | 2.5, 3.1, 5.4, 6.0 |
| Acute chest syndrome | 3 | SS | 4.8, 5.5, 5.8 |
| Multiorgan failure syndrome | 2 | SS | 4.8, 14.8 |
| H influenzae type b sepsis | 1 | SS | 1.9 |
| Myocardial infarction | 1 | SS | 13.7 |
| Complications of recurrent strokes | 1 | SS | 7.8 |
| Ceftriaxone-induced hemolysis | 1 | SS | 2.0 |
| Multifactorial | 2 | SS | 0.9, 4.0 |
| Total | 15 | 4.8* | |
| Probably unrelated to SCD | |||
| Motor vehicle collision | 2 | SS, SC | 1.8, 1.9 |
| Drowning | 1 | SS | 1.2 |
| Complex congenital heart disease (CHD) | 1 | SS | 1.0 |
| Acute viral myocarditis | 1 | SS | 1.1 |
| Down syndrome, Hirschsprung disease, complex CHD | 1 | SS | 5.2 |
| Glutaric acidemia type 2 | 1 | SS | 12.1 |
| Closed head injury | 1 | SS | 17.1 |
| γδ-T-cell lymphoma | 1 | SC | 12.1 |
| Metabolic disorder | 1 | Sβ+ | 1.7 |
| Total | 10 | 1.9* |
Median age