Table 3.

Expression of surface activation markers (CD23, CD25, CD69, and HLA-DR) on eosinophils from unaffected family members (NLs) and patients with FE, HES, or parasitic infections (PARAs)


Patient group

GM % CD23 (range)

GM % CD25 (range)

GM % CD40 (range)

GM % CD69 (range)

GM % HLA-DR (range)
HES, n = 7   1.28 (0.4-1.8)   4.34 (1.1-22.5)   0.66 (0.4-1.2)   5.64 (1.3-18.5)   3.91 (1.9-33.7)  
FE, n = 14   1.87 (0.6-9.8)   0.66* (0.2-1.2)   0.72 (0.3-1.3)   2.88 (0.3-9.1)   6.37 (1.3-38.2)  
NL, n = 14   2.52 (0.3-10.3)   0.12 (0.001-1.1)   0.43 (0.001-2.5)   0.69 (0.3-1.7)   2.96 (0.9-15.8)  
PARA, n = 9
 
1.15 (0.3-5.2)
 
0.62 (0.001-6)
 
0.48 (0.1-0.9)
 
3.02 (0.2-13.6)
 
6.05 (1.1-41.6)
 

Patient group

GM % CD23 (range)

GM % CD25 (range)

GM % CD40 (range)

GM % CD69 (range)

GM % HLA-DR (range)
HES, n = 7   1.28 (0.4-1.8)   4.34 (1.1-22.5)   0.66 (0.4-1.2)   5.64 (1.3-18.5)   3.91 (1.9-33.7)  
FE, n = 14   1.87 (0.6-9.8)   0.66* (0.2-1.2)   0.72 (0.3-1.3)   2.88 (0.3-9.1)   6.37 (1.3-38.2)  
NL, n = 14   2.52 (0.3-10.3)   0.12 (0.001-1.1)   0.43 (0.001-2.5)   0.69 (0.3-1.7)   2.96 (0.9-15.8)  
PARA, n = 9
 
1.15 (0.3-5.2)
 
0.62 (0.001-6)
 
0.48 (0.1-0.9)
 
3.02 (0.2-13.6)
 
6.05 (1.1-41.6)
 
*

P < .01 FE compared with NL or HES, Mann-Whitney U test

P = .02 FE compared with NL, Mann-Whitney U test

P < .01 FE compared with NL, Mann-Whitney U test

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