Plasma lipids
Genotype . | Cholesterol, mM . | Triglycerides, mM . |
|---|---|---|
| Uninduced | ||
| LRPflox/floxLDLR-/-APOE-/- | 25.9 ± 4.5 | 2.5 ± 1.1 |
| MX1Cre+LRPflox/floxLDLR-/-APOE-/- | 28.1 ± 6.2 | 2.6 ± 1.1 |
| pl:pC induced | ||
| LRPflox/floxLDLR-/-APOE-/- | 23.4 ± 6.3 | 2.2 ± 0.8 |
| MX1Cre+LRPflox/floxLDLR-/-APOE-/- | 17.1 ± 5.2* | 1.1 ± 0.5* |
Genotype . | Cholesterol, mM . | Triglycerides, mM . |
|---|---|---|
| Uninduced | ||
| LRPflox/floxLDLR-/-APOE-/- | 25.9 ± 4.5 | 2.5 ± 1.1 |
| MX1Cre+LRPflox/floxLDLR-/-APOE-/- | 28.1 ± 6.2 | 2.6 ± 1.1 |
| pl:pC induced | ||
| LRPflox/floxLDLR-/-APOE-/- | 23.4 ± 6.3 | 2.2 ± 0.8 |
| MX1Cre+LRPflox/floxLDLR-/-APOE-/- | 17.1 ± 5.2* | 1.1 ± 0.5* |
Data are shown as means ± SD.
P < .05, significantly different from LRPflox/floxLDLR-/-APOE-/- mice at 4 weeks after pl:pC induction.