Table 3.

NK-cell content in PB and BM of patients after allogeneic SCT



PB NK cells

BM NK cells

% TNCs
× 10-4/mL
% TNCs
× 10-4/mL
Donors (n = 13/6)   3.31 ± 0.74   19.46 ± 4.35   0.76 ± 0.24   11.08 ± 3.01  
Patients after SCT     
    Day 7 (n = 5/0)   1.98 ± 1.6   0.50 ± 0.34*  ND   ND  
    Day 14 (n = 16/8)   1.84 ± 0.44  6.05 ± 1.82*  0.97 ± 0.30   8.53 ± 2.13  
    Day 30 (n = 16/14)   1.64 ± 0.22  10.62 ± 2.30  0.99 ± 0.30   8.87 ± 3.47  
    Day 90 (n = 15/12)   3.09 ± 0.73   8.20 ± 1.83  1.18 ± 0.36   9.77 ± 2.66  
    Day 180 (n = 9/7)
 
3.08 ± 0.64
 
12.72 ± 2.15
 
1.35 ± 0.31
 
13.68 ± 5.00
 


PB NK cells

BM NK cells

% TNCs
× 10-4/mL
% TNCs
× 10-4/mL
Donors (n = 13/6)   3.31 ± 0.74   19.46 ± 4.35   0.76 ± 0.24   11.08 ± 3.01  
Patients after SCT     
    Day 7 (n = 5/0)   1.98 ± 1.6   0.50 ± 0.34*  ND   ND  
    Day 14 (n = 16/8)   1.84 ± 0.44  6.05 ± 1.82*  0.97 ± 0.30   8.53 ± 2.13  
    Day 30 (n = 16/14)   1.64 ± 0.22  10.62 ± 2.30  0.99 ± 0.30   8.87 ± 3.47  
    Day 90 (n = 15/12)   3.09 ± 0.73   8.20 ± 1.83  1.18 ± 0.36   9.77 ± 2.66  
    Day 180 (n = 9/7)
 
3.08 ± 0.64
 
12.72 ± 2.15
 
1.35 ± 0.31
 
13.68 ± 5.00
 

All numbers are expressed as mean ± SEM; % TNCs is percent of total nucleated cells. n indicates number of PB/BM samples analyzed at each time point; ND, not done.

*

P < .005 compared with healthy controls.

P < .05 compared with healthy controls.

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