Absolute levels of transcripts for different AHI-1 isoforms in subpopulations of cells in normal BM and chronic-phase CML samples
Phenotype and origin of cells . | No. of transcripts/μg RNA × 104 (fold change vs NBM) . | . | . | ||
|---|---|---|---|---|---|
| . | Isoform I . | Isoform II . | Isoform III . | ||
| Lin-CD34+CD38- | |||||
| NBM | 0.5 ± 0.06 | 0.15 ± 0.03 | 1.05 ± 0.02 | ||
| CML | 15.6 ± 0.3 (31) | 4.8 ± 0.6 (32) | 0.85 ± 0.15 (0.8) | ||
| Lin-CD34+CD38+ | |||||
| NBM | 0.27 ± 0.05 | 0.05 ± 0.01 | 0.50 ± 0.08 | ||
| CML | 1.48 ± 0.12 (5.4) | 0.16 ± 0.03 (3.2) | 1.00 ± 0.12 (2) | ||
| Lin-CD34+ | |||||
| NBM | 0.35 ± 0.09 | 0.06 ± 0.01 | 0.65 ± 0.10 | ||
| CML | 1.6 ± 0.25 (4.5) | 0.19 ± 0.03 (3.2) | 1.60 ± 0.30 (2.5) | ||
| Lin+CD34- | |||||
| NBM | 0.1 ± 0.03 | 0.01 ± 0.00 | 0.20 ± 0.02 | ||
| CML | 0.45 ± 0.08 (4.5) | 0.05 ± 0.01 (5) | 0.65 ± 0.08 (3.3) | ||
Phenotype and origin of cells . | No. of transcripts/μg RNA × 104 (fold change vs NBM) . | . | . | ||
|---|---|---|---|---|---|
| . | Isoform I . | Isoform II . | Isoform III . | ||
| Lin-CD34+CD38- | |||||
| NBM | 0.5 ± 0.06 | 0.15 ± 0.03 | 1.05 ± 0.02 | ||
| CML | 15.6 ± 0.3 (31) | 4.8 ± 0.6 (32) | 0.85 ± 0.15 (0.8) | ||
| Lin-CD34+CD38+ | |||||
| NBM | 0.27 ± 0.05 | 0.05 ± 0.01 | 0.50 ± 0.08 | ||
| CML | 1.48 ± 0.12 (5.4) | 0.16 ± 0.03 (3.2) | 1.00 ± 0.12 (2) | ||
| Lin-CD34+ | |||||
| NBM | 0.35 ± 0.09 | 0.06 ± 0.01 | 0.65 ± 0.10 | ||
| CML | 1.6 ± 0.25 (4.5) | 0.19 ± 0.03 (3.2) | 1.60 ± 0.30 (2.5) | ||
| Lin+CD34- | |||||
| NBM | 0.1 ± 0.03 | 0.01 ± 0.00 | 0.20 ± 0.02 | ||
| CML | 0.45 ± 0.08 (4.5) | 0.05 ± 0.01 (5) | 0.65 ± 0.08 (3.3) | ||