Table 7. Summary of patients who... | American Society of Hematology

Table 7.

Summary of patients who received antiresorptive therapy and/or who suffered from osteoporotic fracture after stem cell transplantation (in order of length of follow-up)

Pt. no.	Therapy started (mo)*	Occurrence of fracture	Fracture event (mo)	Clinical data and time of follow-up (mo)
01	Yes (3)†	Yes	Th 10-12, L1-2 (3)∥	28, female, CML, death¶ (9)
02	No	Yes	Th 11-12, L1 (4)∥	50, female, AML, death# (10)
03	Yes (21)*	No	—	35, female, AML, death¶ (22)
04	Yes (12)*	Yes	Femoral neck (22)∥	40, female, ALL, death# (26)
05	Yes (6)*	No	—	46, female, CML, death# (34)
06	Yes (9)*	No	—	16, female, AML, alive (41)
07	Yes (4)*	No	—	28, female, AML, alive (43)
08	Yes (8)*	No	—	38, female, CML, alive (44)
09	Yes (19)*	No	—	39, female, MDS, alive (44)
10	No	Yes	Femoral neck (38)∥	45, female, CML, death# (44)
11	Yes (29)†	No	Osteoporotic pain syndrome§	42, male, CML, alive (45)
12	Yes (14)*	No	—	49, female, CML, alive (45)
13	Yes (3)*	No	—	43, male, NHL, alive (46)
14	Yes (12)*	No	—	51, male, CML, alive (47)
15	Yes (32)‡	No	—	37, male, CML, alive (48)
16	No	Yes	L4 (11)∥	32, female, CML, alive (50)
17	Yes (5)*	No	—	20, male, MDS, alive (51)
18	Yes (16)‡	No	—	37, female, MDS, alive (52)
19	Yes (8)†	Yes	Th 12, L1 (8)∥	22, male, CML, alive (56)
20	Yes (27)*	No	—	50, male, CML, alive (56)
21	Yes (9)†	No	Pre-existing osteoporosis§	31, female, CML, alive (56)
22	Yes (34)*	No	—	47, female, CML, alive (60)
23	Yes (29)*	No	—	37, female, AML, alive (62)
24	Yes (58)*	No	—	35, male, CML, alive (67)
25	Yes (23)*	No	—	35, male, CML, death# (68)
26	Yes (37)*	No	—	19, male, AML, alive (70)
27	Yes (19)*	No	—	28, male, CML, alive (73)
28	Yes (34)†	Yes	Femoral head (34)∥	42, male, CML, alive (74)
29	Yes (28)*	No	—	54, female, CML, alive (77)
30	No	Yes	Th 11 (14)	18, male, ALL, alive (78)
31	Yes (59)*	No	—	42, male, NHL, alive (80)
32	Yes (67)†	Yes	Ribs, L1, L3 (62)∥	40, male, CML, alive (81)
33	Yes (39)*	No	—	26, female, AML, alive (82)
34	Yes (73)†	Yes	8th rib (53)∥	39, male, CML, alive (83)
35	Yes (50)*	No	—	55, female, CML, alive (93)

Pt. no.	Therapy started (mo)*	Occurrence of fracture	Fracture event (mo)	Clinical data and time of follow-up (mo)
01	Yes (3)†	Yes	Th 10-12, L1-2 (3)∥	28, female, CML, death¶ (9)
02	No	Yes	Th 11-12, L1 (4)∥	50, female, AML, death# (10)
03	Yes (21)*	No	—	35, female, AML, death¶ (22)
04	Yes (12)*	Yes	Femoral neck (22)∥	40, female, ALL, death# (26)
05	Yes (6)*	No	—	46, female, CML, death# (34)
06	Yes (9)*	No	—	16, female, AML, alive (41)
07	Yes (4)*	No	—	28, female, AML, alive (43)
08	Yes (8)*	No	—	38, female, CML, alive (44)
09	Yes (19)*	No	—	39, female, MDS, alive (44)
10	No	Yes	Femoral neck (38)∥	45, female, CML, death# (44)
11	Yes (29)†	No	Osteoporotic pain syndrome§	42, male, CML, alive (45)
12	Yes (14)*	No	—	49, female, CML, alive (45)
13	Yes (3)*	No	—	43, male, NHL, alive (46)
14	Yes (12)*	No	—	51, male, CML, alive (47)
15	Yes (32)‡	No	—	37, male, CML, alive (48)
16	No	Yes	L4 (11)∥	32, female, CML, alive (50)
17	Yes (5)*	No	—	20, male, MDS, alive (51)
18	Yes (16)‡	No	—	37, female, MDS, alive (52)
19	Yes (8)†	Yes	Th 12, L1 (8)∥	22, male, CML, alive (56)
20	Yes (27)*	No	—	50, male, CML, alive (56)
21	Yes (9)†	No	Pre-existing osteoporosis§	31, female, CML, alive (56)
22	Yes (34)*	No	—	47, female, CML, alive (60)
23	Yes (29)*	No	—	37, female, AML, alive (62)
24	Yes (58)*	No	—	35, male, CML, alive (67)
25	Yes (23)*	No	—	35, male, CML, death# (68)
26	Yes (37)*	No	—	19, male, AML, alive (70)
27	Yes (19)*	No	—	28, male, CML, alive (73)
28	Yes (34)†	Yes	Femoral head (34)∥	42, male, CML, alive (74)
29	Yes (28)*	No	—	54, female, CML, alive (77)
30	No	Yes	Th 11 (14)	18, male, ALL, alive (78)
31	Yes (59)*	No	—	42, male, NHL, alive (80)
32	Yes (67)†	Yes	Ribs, L1, L3 (62)∥	40, male, CML, alive (81)
33	Yes (39)*	No	—	26, female, AML, alive (82)
34	Yes (73)†	Yes	8th rib (53)∥	39, male, CML, alive (83)
35	Yes (50)*	No	—	55, female, CML, alive (93)

Antiresorptive treatment started for prevention of fracture (*), occurrence of fracture (†), or avascular necrosis (‡).

Pt indicates patient; —, no fracture event.

Osteoporotic fractures.

∥

Harmful events other than fracture.

Death due to infectious complications.

Death due to disease recurrence.

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