Patient characteristics of 280 patients undergoing allogeneic stem cell transplantation
. | Percentage . | n . |
|---|---|---|
| Preparative regimen* | ||
| TBI + Cy | 79 | 221 |
| CyBuThio | 11 | 31 |
| Other | 10 | 28 |
| Diagnosis | ||
| CML | 55 | 154 |
| AML | 24 | 67 |
| ALL | 8 | 22 |
| MDS | 7 | 20 |
| NHL | 2 | 6 |
| Other | 4 | 11 |
| Source of stem cells | ||
| BM | 58 | 161 |
| PBSC | 42 | 119 |
| HLA match | ||
| Related donor identical | 50.7 | 142 |
| Related donor mismatch | 14.6 | 41 |
| Unrelated donor identical | 30 | 84 |
| Unrelated donor mismatch | 4.6 | 13 |
| Sex match | ||
| Male to male | 37 | 104 |
| Male to female | 19 | 53 |
| Female to female | 21 | 59 |
| Female to male | 23 | 64 |
. | Percentage . | n . |
|---|---|---|
| Preparative regimen* | ||
| TBI + Cy | 79 | 221 |
| CyBuThio | 11 | 31 |
| Other | 10 | 28 |
| Diagnosis | ||
| CML | 55 | 154 |
| AML | 24 | 67 |
| ALL | 8 | 22 |
| MDS | 7 | 20 |
| NHL | 2 | 6 |
| Other | 4 | 11 |
| Source of stem cells | ||
| BM | 58 | 161 |
| PBSC | 42 | 119 |
| HLA match | ||
| Related donor identical | 50.7 | 142 |
| Related donor mismatch | 14.6 | 41 |
| Unrelated donor identical | 30 | 84 |
| Unrelated donor mismatch | 4.6 | 13 |
| Sex match | ||
| Male to male | 37 | 104 |
| Male to female | 19 | 53 |
| Female to female | 21 | 59 |
| Female to male | 23 | 64 |
Mean age (y) range, 16 to 59 (37.6 ± 10.2). Ratio of female to male 110:170.
TBI indicates total body irradiation; Cy, cyclophosphamide; Bu, busulfane; Thio, thiotepa; CML, chronic myeloid leukemia; AML, acute myeloid leukemia; ALL, acute lymphoblastic leukemia; MDS, myelodysplasia; NHL, non-Hodgkin lymphoma; BM, bone marrow; PBSC, peripheral blood stem cell; and NA, not applicable.
For description of conditioning regimens before transplantation, see Table 2.