Thymectomy does not affect CD45 congenic marrow engraftment in nonirradiated mice
. | % Donor cells 4 weeks after BMT . | . | . | . | |||
---|---|---|---|---|---|---|---|
. | . | Spleen . | . | . | |||
. | BM . | CD4 . | CD8 . | B220 . | |||
BMT, no TI | 22.40 ± 8.05 | 2.07 ± 1.01 | 2.33 ± 0.61 | 12.21 ± 5.38 | |||
ATX, BMT, no TI | |||||||
1 | 26.58 | 1.26 | 3.96 | 17.57 | |||
2 | 28.82 | 3.62 | 5.18 | 14.14 |
. | % Donor cells 4 weeks after BMT . | . | . | . | |||
---|---|---|---|---|---|---|---|
. | . | Spleen . | . | . | |||
. | BM . | CD4 . | CD8 . | B220 . | |||
BMT, no TI | 22.40 ± 8.05 | 2.07 ± 1.01 | 2.33 ± 0.61 | 12.21 ± 5.38 | |||
ATX, BMT, no TI | |||||||
1 | 26.58 | 1.26 | 3.96 | 17.57 | |||
2 | 28.82 | 3.62 | 5.18 | 14.14 |
Populations are as follows: n = 4 for BMT, no TI group (mean ± SD is shown); and n = 2 for ATX, BMT, no TI group (each row represents an individual animal in this group). For bone marrow transplantation (BMT), 2 × 108 CD45.2 B6 bone marrow cells were given to untreated CD45.1 B6 recipients. TI indicates thymic irradiation; and ATX, adult thymectomy.