Table 7.

Cox regression analysis of survival time from diagnosis and study entry in 88 risk-matched patients




Hazard ratio for death (95% CI)
Overall survival from diagnosis  
Treatment SHDT   0.38 (0.15-0.97)* 
11q deletion   3.82 (1.51-9.67)* 
Stage at diagnosis B   0.88 (0.36-2.11)  
Stage at diagnosis C   1.69 (0.35-8.13)  
VH mutated   0.44 (0.15-1.28)  
Age at diagnosis   1.50 (0.54-4.18)  
Overall survival from study entry  
Treatment SHDT   0.38 (0.15-0.93)* 
11q deletion   4.91 (1.84-13.08)* 
Lymphocyte count at study entry higher than 50 × 109/L   0.43 (0.17-1.10)  
Stage at study entry B   1.65 (0.44-6.10)  
Stage at study entry C   5.90 (1.42-24.44)* 
VH mutated   0.74 (0.23-2.41)  
Age at study entry   1.19 (0.48-2.93)  
Chemotherapeutic pretreatment at study entry
 
2.25 (0.91-5.52)
 



Hazard ratio for death (95% CI)
Overall survival from diagnosis  
Treatment SHDT   0.38 (0.15-0.97)* 
11q deletion   3.82 (1.51-9.67)* 
Stage at diagnosis B   0.88 (0.36-2.11)  
Stage at diagnosis C   1.69 (0.35-8.13)  
VH mutated   0.44 (0.15-1.28)  
Age at diagnosis   1.50 (0.54-4.18)  
Overall survival from study entry  
Treatment SHDT   0.38 (0.15-0.93)* 
11q deletion   4.91 (1.84-13.08)* 
Lymphocyte count at study entry higher than 50 × 109/L   0.43 (0.17-1.10)  
Stage at study entry B   1.65 (0.44-6.10)  
Stage at study entry C   5.90 (1.42-24.44)* 
VH mutated   0.74 (0.23-2.41)  
Age at study entry   1.19 (0.48-2.93)  
Chemotherapeutic pretreatment at study entry
 
2.25 (0.91-5.52)
 

For age, hazard ratios and confidence intervals (CIs) are computed for 10-year increments.

*

P < .05.

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