Effect of dietary iron level and hepcidin on proportional mucosal transfer of iron
Diet . | Treatment . | Mucosal transfer, % of total uptake . |
|---|---|---|
| Iron replete | Control | 63.4 ± 3.9 |
| Iron replete | Hepcidin | 57.2 ± 6.8 |
| Iron deficient | Control | 80.3 ± 1.4 |
| Iron deficient | Hepcidin | 82.6 ± 0.7 |
Diet . | Treatment . | Mucosal transfer, % of total uptake . |
|---|---|---|
| Iron replete | Control | 63.4 ± 3.9 |
| Iron replete | Hepcidin | 57.2 ± 6.8 |
| Iron deficient | Control | 80.3 ± 1.4 |
| Iron deficient | Hepcidin | 82.6 ± 0.7 |
Iron deficiency was induced by feeding the mice a low iron diet for 3 weeks. Iron-replete controls received the same diet supplemented with iron. Mice were injected with 0.15 M NaCl (controls) or hepcidin (50 μg single injection) on each of 2 consecutive days, 24 hours before they were killed. Statistical analysis is shown in Table 3.