Effect of hepcidin on body weights, iron stores, and hemoglobin in mice
Treatment . | n . | Body weight, g . | Hemoglobin, g/L . | Liver nonheme iron, nmol/mg . |
---|---|---|---|---|
Control | 10 | 38.8 ± 0.6 | 156 ± 05 | 1.82 ± 0.19 |
10 μg hepcidin | 6 | 37.2 ± 1.4 | 154 ± 07 | 1.67 ± 0.28 |
100 μg hepcidin | 6 | 36.4 ± 1.0* | 156 ± 04 | 1.59 ± 0.15 |
Treatment . | n . | Body weight, g . | Hemoglobin, g/L . | Liver nonheme iron, nmol/mg . |
---|---|---|---|---|
Control | 10 | 38.8 ± 0.6 | 156 ± 05 | 1.82 ± 0.19 |
10 μg hepcidin | 6 | 37.2 ± 1.4 | 154 ± 07 | 1.67 ± 0.28 |
100 μg hepcidin | 6 | 36.4 ± 1.0* | 156 ± 04 | 1.59 ± 0.15 |
Mice were injected daily for 3 days with 0.15 M NaCl (controls) or hepcidin dissolved in 0.15 M NaCl.
Data are expressed as means ± SEM for the number of mice per group.
P < .05 compared with appropriate control.