Table 1.

Effect of hepcidin on body weights, iron stores, and hemoglobin in mice


Treatment

n

Body weight, g

Hemoglobin, g/L

Liver nonheme iron, nmol/mg
Control   10   38.8 ± 0.6   156 ± 05   1.82 ± 0.19  
10 μg hepcidin   6   37.2 ± 1.4   154 ± 07   1.67 ± 0.28  
100 μg hepcidin
 
6
 
36.4 ± 1.0*
 
156 ± 04
 
1.59 ± 0.15
 

Treatment

n

Body weight, g

Hemoglobin, g/L

Liver nonheme iron, nmol/mg
Control   10   38.8 ± 0.6   156 ± 05   1.82 ± 0.19  
10 μg hepcidin   6   37.2 ± 1.4   154 ± 07   1.67 ± 0.28  
100 μg hepcidin
 
6
 
36.4 ± 1.0*
 
156 ± 04
 
1.59 ± 0.15
 

Mice were injected daily for 3 days with 0.15 M NaCl (controls) or hepcidin dissolved in 0.15 M NaCl.

Data are expressed as means ± SEM for the number of mice per group.

*

P < .05 compared with appropriate control.

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